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ECA3 protein (Arabidopsis thaliana) - STRING interaction network
"ECA3" - Ca2+-transporting ATPase in Arabidopsis thaliana
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Predicted Interactions
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textmining
co-expression
protein homology
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ECA3Ca2+-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to an endomembrane compartment. Involved in calcium-enhanced root growth, in tolerance to toxic levels of manganese and in secretory processes. Has a crucial role in manganese nutrition, but is not involved in transporting copper, iron or zinc (998 aa)    
Predicted Functional Partners:
HMA3
Heavy metal atpase 3 (542 aa)
     
  0.883
NRAMP1
Metal transporter Nramp1; High affinity manganese (Mn) transporter involved in Mn acquisition from the soil. Required for Mn uptake into the root in conditions of low Mn availability. Can transport iron (Fe), cadmium (Cd) and cobalt (Co) (532 aa)
     
 
  0.838
NRAMP3
Metal transporter Nramp3; Vacuolar metal transporter involved in intracellular metal homeostasis. Can transport iron (Fe), manganese (Mn) and cadmium (Cd). Regulates metal accumulation under Fe starvation. Acts redundantly with NRAMP4 to mobilize vacuolar Fe and provide sufficient Fe during seed germination. In association with NRAMP4, required for optimal growth and photosynthesis under Mn deficiency. Exports Mn from vacuoles in leaf mesophyll cells, making Mn available for functional photosystem II in chloroplasts. Involved in basal resistance to the bacterial pathogen E.chrysanthemi (509 aa)
     
 
  0.837
HMA4
Heavy metal atpase 4; Involved in cadmium/zinc transport (1172 aa)
     
0.837
HMA2
Heavy metal atpase 2; Plays an important role in zinc transport and homeostasis. Could also be involved in cadmium detoxification (951 aa)
     
0.822
RAN1
RESPONSIVE-TO-ANTAGONIST 1; Involved in copper import into the cell. Essential for ethylene signaling, which requires copper. Acts by delivering copper to create functional hormone receptors (1001 aa)
     
0.821
HMA8
P-type ATPase; Mediates copper transfer across the chloroplast thylakoid membrane. Required for copper delivery into the thylakoids lumen, which is essential for the function of copper proteins (883 aa)
     
0.817
HMA1
Heavy metal atpase 1; Involved in cadmium/zinc transport (819 aa)
     
0.814
HMA5
Heavy metal atpase 5; Involved in copper import into the cell. May play a role in copper detoxification in roots (995 aa)
     
0.811
MTP11
Putative Mn-specific cation diffusion facilitator transporter; Cation/proton antiporter involved in endogenous manganese tolerance probably through vesicular trafficking and exocytosis (394 aa)
         
  0.809
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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