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AT1G10250 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G10250" - Paired amphipathic helix Sin3-like protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G10250Paired amphipathic helix Sin3-like protein; BEST Arabidopsis thaliana protein match is- SIN3-like 6 (TAIR-AT1G10450.1); Has 310 Blast hits to 310 proteins in 86 species- Archae - 0; Bacteria - 0; Metazoa - 174; Fungi - 23; Plants - 97; Viruses - 0; Other Eukaryotes - 16 (source- NCBI BLink) (77 aa)    
Predicted Functional Partners:
AT3G52250
Duplicated homeodomain-like superfamily protein; Encodes a protein with a putative role in mRNA splicing (1656 aa)
     
 
  0.813
AT3G13350
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (319 aa)
     
 
  0.766
AT1G76110
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (338 aa)
     
 
  0.766
AT1G55650
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (337 aa)
     
 
  0.766
AT1G04880
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (448 aa)
     
 
  0.766
ELF6
Zinc finger (C2H2 type) family protein / transcription factor jumonji (jmj) family protein; Early Flowering 6 (ELF6) encodes a Jumonji N/C and zinc finger domain-containing protein that acts as a repressor in the photoperiod pathway. ELF6 interacts with BES1 in a Y2H assay, in vitro, and in Arabidosis protoplasts (based on BiFC). ELF6 may play a role in brassinosteroid signaling by affecting histone methylation in the promoters of BR-responsive genes; Belongs to the JHDM3 histone demethylase family (1340 aa)
     
 
  0.743
REF6
Lysine-specific demethylase REF6; Histone demethylase that demethylates ’Lys-27’ (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me. Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay. Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli. Binds DNA via its four zinc fingers in a sequence-specific manner, 5’-CTCTGYTY-3’, to promote the demethylation of H3K27me3 and the regulation of organ boundary formation. Involved in the regulation of flowering tim [...] (1360 aa)
     
 
  0.743
HAT3.1
Homeodomain-like protein with RING/FYVE/PHD-type zinc finger domain; Encodes a member of the PHD-finger homeodomain protein family. The HAT3.1 homeodomain is highly divergent in sequence even at positions that are almost invariable among homeodomains. HAT3.1 shows a preference for the sequence T(A/G)(A/C)ACCA, different from those bound by other homeodomains; Belongs to the PHD-associated homeobox family (723 aa)
     
 
  0.700
PRHA
Homeodomain protein (PRHA). Expression of the gene differs in various vegetative and floral plant tissues and is positively influenced by the phytohormone auxin. It is often associated with regions of developing vascular tissue. The prha promoter is highly responsive to the synthetic auxin, naphthalene acetic acid, in transient assays using tobacco protoplasts. The PRHA protein has the capacity to bind to TAATTG core sequence elements but requires additional adjacent bases for high-affinity binding; Belongs to the PHD-associated homeobox family (796 aa)
     
 
  0.681
ING1
RING/FYVE/PHD zinc finger superfamily protein; Histone-binding component that specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes (234 aa)
     
 
  0.609
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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