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CPISCA protein (Arabidopsis thaliana) - STRING interaction network
"CPISCA" - Iron-sulfur assembly protein IscA in Arabidopsis thaliana
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Predicted Interactions
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textmining
co-expression
protein homology
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CPISCAIron-sulfur assembly protein IscA; Involved in the assembly of chloroplastic iron-sulfur proteins. Is able to transfer iron-sulfur clusters to apo- ferredoxin (180 aa)    
Predicted Functional Partners:
MFDX2
Ferredoxin 2; Associates with the adrenodoxin reductase MFDR to form an efficient low potential electron transfer chain that is able to reduce cytochrome C (197 aa)
   
 
  0.963
CPSUFE
SufE-like protein; Participates in cysteine desulfurization mediated by NFS2 in chloroplast and NIFS1 in mitochondrion (PubMed-16437155). Activates the cysteine desulfurase activity of NFS2 (PubMed-16455656). Cysteine desulfurization mobilizes sulfur from L-cysteine to yield L-alanine and supplies the inorganic sulfur for iron-sulfur (Fe-S) cluster formation. Glutaredoxins regulate SUFE1 activity by inducing its reduction and deglutathionylation (PubMed-24203231) (371 aa)
   
 
  0.962
ISU1
SufE/NifU family protein; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed-15507320, PubMed-17417719). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3). In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the reci [...] (167 aa)
   
   
  0.950
NAP7
Non-intrinsic ABC protein 7; Essential protein. Required during embryo development, especially at early stages. Involved in chloroplast differentiation (338 aa)
   
 
  0.946
CPNIFS
Cysteine desulfurase 2; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine (PubMed-12033984, PubMed-16455656). Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (PubMed-15480755, PubMed-17372218). Required for the maturation of all plastidic Fe-S proteins and, thus, essential for plant growth (PubMed-17372218) (463 aa)
   
 
  0.942
MFDX1
Mitochondrial ferredoxin 1; Associates in vitro with the adrenodoxin reductase MFDR to form an efficient low potential electron transfer chain that is able to reduce cytochrome C (PubMed-12714594, PubMed-13677469). Functions as accessory mitochondrial protein involved with BIO2 in the plant biotin synthase reaction (PubMed-12714594) (197 aa)
   
 
  0.937
FdC1
Ferredoxin (154 aa)
   
 
  0.931
NFS1
Cysteine desulfurase 1; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (453 aa)
   
   
  0.901
AT5G06410
Molecular chaperone HscB (252 aa)
   
   
  0.900
QS
Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. Can complement nadA-deficient E.coli mutant. Essential for the de novo synthesis of NAD. Participates also in cysteine desulfurization mediated by NFS2. Can activate the cysteine desulfurase activity of NFS2 in vitro (718 aa)
   
   
  0.888
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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