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AT1G10520 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G10520" - DNA polymerase {lambda} in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
AT1G10520DNA polymerase {lambda} (529 aa)    
Predicted Functional Partners:
PCNA2
Proliferating cell nuclear antigen 2; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (By similarity). May be involved in UV resistance (264 aa)
       
  0.996
PCNA1
Proliferating cellular nuclear antigen 1; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (263 aa)
     
  0.992
LIG1
DNA ligase 1; Essential protein. DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Involved in repair of both single strand breaks (SSBs) and double strand breaks (DSBs). Required in the endosperm for embryogenesis, probably to repair DNA-breaks generated by DME (790 aa)
   
  0.962
PARP1
POLY(ADP-RIBOSE) POLYMERASE 1; Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity) (983 aa)
     
  0.958
AT5G26680
Flap endonuclease-1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (453 aa)
     
  0.957
EMB2780
DNA polymerase delta subunit 1; This polymerase possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3’- to 5’-direction (1112 aa)
     
  0.949
AT1G49250
ATP-dependent DNA ligase (657 aa)
     
  0.948
AT3G48425
DNAse I-like superfamily protein; Apurinic/apyrimidinic (AP) endonuclease involved in active DNA demethylation and gene imprinting (PubMed-25569774). According to a report, displays also an in vitro 3’-phosphatase activity (PubMed-25569774). According to another report, has no in vitro 3’-phosphatase activity (PubMed-25228464). Catalyzes the conversion of the 3’-blocking groups 3’-phosphor-alpha,beta- unsaturated aldehyde (3’-PUA) generated by ROS1 to 3’-OH (PubMed-25228464, PubMed-25569774). Has a strong non-specific affinity to DNA (PubMed-25228464). Redundant with APE2 and at least [...] (364 aa)
     
  0.947
ARP
Apurinic endonuclease-redox protein; Repairs oxidative DNA damages, seems also to act as a redox factor (PubMed-7512729). Is multifunctional and may be involved both in DNA repair and in the regulation of transcription (PubMed-7512729). Exhibits apurinic/apyrimidinic (AP) endonuclease activity (PubMed-25569774, PubMed-21781197, PubMed-25228464). Catalyzes the conversion of 3’-phosphor-alpha,beta-unsaturated aldehyde (3’-PUA) to 3’-OH (PubMed-25228464). May be involved in base excision repair in chloroplasts (PubMed-19372224). According to a report, has a significant in vitro 3’-phospha [...] (536 aa)
     
  0.944
APTX
Aprataxin (912 aa)
     
  0.935
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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