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CYP71A18 protein (Arabidopsis thaliana) - STRING interaction network
"CYP71A18" - Cytochrome P450, family 71, subfamily A, polypeptide 18 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
CYP71A18Cytochrome P450, family 71, subfamily A, polypeptide 18; Putative cytochrome P450 (504 aa)    
Predicted Functional Partners:
CYP79B3
Cytochrome P450, family 79, subfamily B, polypeptide 3; Encodes a cytochrome P450. Involved in tryptophan metabolism. Converts Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates (543 aa)
   
   
0.912
CYP79B2
Cytochrome P450, family 79, subfamily B, polypeptide 2; Converts tryptophan to indole-3-acetaldoxime, a precursor for tryptophan-derived glucosinolates and indole-3- acetic acid (IAA). Involved in the biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitrile (4- OH-ICN), a cyanogenic metabolite required for inducible pathogen defense; Belongs to the cytochrome P450 family (541 aa)
   
   
0.911
CYP83B1
Cytochrome P450, family 83, subfamily B, polypeptide 1; Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl- thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p- hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (499 aa)
   
   
0.905
NIT3
Nitrilase 3; This enzyme catalyzes the hydrolysis of indole-3-acetonitrile (IAN) to indole-3-acetic acid (IAA) (EC 3.5.5.1) and IAN to indole-3-acetamide (IAM) at lower levels. It is the only one of the four Arabidopsis nitrilases whose mRNA levels are strongly induced when plants experience sulphur deprivation. This enzyme likely participates in other non-auxin-related metabolic pathways (346 aa)
         
    0.900
NIT1
Nitrilase 1; Mutants are resistant to indole-3-acetonitrile (IAN). NIT1 catalyzes the terminal activation step in indole-acetic acid biosynthesis. Predominantly expressed isoform of nitrilase isoenzyme family. Aggregation of NIT1 in cells directly abutting wound sites is one of the earliest events associated with wound and herbicide-induced cell death. The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide. It is also involved in the conversion of IAN to IAM (indole-3-acetamide) and other non-auxin-related metabolic processes (346 aa)
         
    0.900
NIT2
Nitrilase 2; Encodes an enzyme that catalyzes the hydrolysis of indole-3-acetonitrile (IAN) to indole-3-acetic acid (IAA) (nitrile aminohydrolase, EC 3.5.5.1) and IAN to indole-3-acetamide (IAM) at lower levels. Mutants have reduced sensitivity to IAN and are sensitive to IAA. This enzyme likely participates in other non-auxin-related metabolic pathways (339 aa)
         
    0.900
CYP71A13
Cytochrome P450, family 71, subfamily A, polypeptide 13; Involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes the conversion of indole-3- acetaldoxime to indole-3-acetonitrile. Required for resistance to A.brassicicola and B.cinerea; Belongs to the cytochrome P450 family (503 aa)
   
 
0.832
CYP71A12
Cytochrome P450, family 71, subfamily A, polypeptide 12; Converts indole-3-acetaldoxime to indole cyanohydrin. Involved in the biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitrile (4-OH-ICN), a cyanogenic metabolite required for inducible pathogen defense; Belongs to the cytochrome P450 family (503 aa)
   
 
0.818
NIC2
Nicotinamidase 2; Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Prevents the accumulation of intracellular nicotinamide, a known inhibitor of poly(ADP-ribose) polymerases (PARP enzymes). May play a role in the regulation of seed germination potential (198 aa)
           
  0.713
TGG3
Thioglucoside glucosidase 3; Is a myrosinase pseudogene that codes for a truncated and frameshifted protein. Although TGG3 apparently is a pseudogene, its mRNA is expressed specifically in stamen and petal according to RT-PCR analysis. Western analysis shows no band of the size expected for a TGG3 protein; Belongs to the glycosyl hydrolase 1 family (439 aa)
         
    0.650
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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