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LEW1 protein (Arabidopsis thaliana) - STRING interaction network
"LEW1" - Undecaprenyl pyrophosphate synthetase family protein in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LEW1Undecaprenyl pyrophosphate synthetase family protein; Encodes a cis-prenyltransferase, involved in dolichol biosynthesis. Wilted leaves in mutants due to cell membrane lesions. Mutants have increased drought tolerance, but hypersensitve to dark stress (254 aa)    
Predicted Functional Partners:
CPT
Dehydrodolichyl diphosphate synthase 1; Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein (303 aa)
     
 
  0.965
FPS1
Farnesyl pyrophosphate synthase 1, mitochondrial; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (384 aa)
   
  0.931
cPT1
Undecaprenyl pyrophosphate synthetase family protein; Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein (295 aa)
     
 
  0.876
FPS2
Farnesyl pyrophosphate synthase 2; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate; Belongs to the FPP/GGPP synthase family (342 aa)
   
  0.850
AT2G23400
Undecaprenyl pyrophosphate synthetase family protein; Contains the following InterPro domains- Di-trans-poly-cis-decaprenylcistransferase-like, conserved site (InterPro-IPR018520), Di-trans-poly-cis-decaprenylcistransferase-like (InterPro-IPR001441); BEST Arabidopsis thaliana protein match is- cis-prenyltransferase (TAIR-AT2G23410.1); Has 35333 Blast hits to 34131 proteins in 2444 species- Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source- NCBI BLink); Belongs to the UPP synthase family (253 aa)
     
 
  0.842
ERA1
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X (CaaX). The beta subunit is responsible for peptide-binding (482 aa)
     
 
  0.782
FTA
Encodes the alpha-subunit shared between protein farnesyltransferase and protein geranylgeranyltransferase-I. Involved in protein prenylation- covalent attachment of the C-15 isoprene farnesyl or the C-20 isoprene geranylgeranyl groups to the C-terminal end of some proteins. Involved in shoot and flower meristem homeostasis, and response to ABA and drought. Also regulates leaf cell shape. Mutant is epistatic to era1 (326 aa)
         
  0.782
AT3G08630
Protein RETICULATA-RELATED 2, chloroplastic; May play a role in leaf development (339 aa)
           
  0.767
LEW3
Encodes a putative alpha-1,2-mannosyltransferase in N-linked glycoprotein (homologous to yeast ALG11). Plays vital roles in cell-wall biosynthesis and abiotic stress response. Located in endoplasmic reticulum membrane; Belongs to the glycosyltransferase 4 family (463 aa)
     
   
  0.741
cPT8
Undecaprenyl pyrophosphate synthetase family protein; Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein; Belongs to the UPP synthase family (271 aa)
     
 
  0.708
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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