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GLX1 protein (Arabidopsis thaliana) - STRING interaction network
"GLX1" - Lactoylglutathione lyase GLX1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GLX1Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (322 aa)    
Predicted Functional Partners:
GLX2-4
Probable hydroxyacylglutathione hydrolase 2, chloroplastic; Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (331 aa)
 
 
  0.992
GLX2-5
Hydroxyacylglutathione hydrolase 2, mitochondrial; Encodes a mitochondrial glyoxalase 2 that can accommodate a number of different metal centers and with the predominant metal center being Fe(III)Zn(II) (324 aa)
 
 
  0.992
GLX2-1
Hydroxyacylglutathione hydrolase 1, mitochondrial; Encodes a predicted mitochondrial glyoxalase GLX2-1. Studies using recombinant protein show that GLX2-1 contains a dinuclear metal binding site, but does not have glyoxalase 2 activity (331 aa)
 
 
  0.992
GLY2
Metallo-hydrolase/oxidoreductase superfamily protein; Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family (258 aa)
   
 
  0.991
GLY3
Persulfide dioxygenase ETHE1 homolog, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) gives rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the [...] (294 aa)
   
   
  0.963
DJ1D
Class I glutamine amidotransferase-like superfamily protein; Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. May be involved in oxidative stress response (388 aa)
   
  0.952
YLS5
Class I glutamine amidotransferase-like superfamily protein; May be involved in oxidative stress response; Belongs to the peptidase C56 family (398 aa)
   
  0.948
DJ1F
Class I glutamine amidotransferase-like superfamily protein; May be involved in oxidative stress response (399 aa)
   
  0.947
OMR1
Threonine dehydratase biosynthetic, chloroplastic; Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia; Belongs to the serine/threonine dehydratase family (592 aa)
       
  0.886
AT1G08110
Lactoylglutathione lyase family protein / glyoxalase I family protein; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (235 aa)
   
 
0.869
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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