• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Hop1 protein (Arabidopsis thaliana) - STRING interaction network
"Hop1" - Stress-inducible protein, putative in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hop1Stress-inducible protein, putative; Mediates the association of the molecular chaperones HSP70 and HSP90. Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity) (572 aa)    
Predicted Functional Partners:
HSP90.1
Heat shock protein 90-1; Functions as a holding molecular chaperone (holdase) which stabilizes unfolding protein intermediates and rapidly releases them in an active form once stress has abated. Functions as a folding molecular chaperone (foldase) that assists the non- covalent folding of proteins in an ATP-dependent manner. Molecular chaperone involved in R gene-mediated disease resistance. Required for full RPS2-mediated resistance through interaction with RAR1. Possesses probably ATPase activity (705 aa)
   
  0.993
Hsp81.4
HEAT SHOCK PROTEIN 81.4; Molecular chaperone which stabilizes unfolding protein intermediates and functions as a folding molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner; Belongs to the heat shock protein 90 family (699 aa)
   
  0.992
HSP81-3
Heat shock protein 90-3; Functions as a holding molecular chaperone (holdase) which stabilizes unfolding protein intermediates and rapidly releases them in an active form once stress has abated. Functions as a folding molecular chaperone (foldase) that assists the non- covalent folding of proteins in an ATP-dependent manner. Regulates RPP4-mediated temperature-dependent cell death and defense responses. May assist SGT1B in the formation of SCF E3 ubiquitin ligase complexes that target the immune receptors SNC1, RPS2 and RPS4 for degradation, to regulate receptor levels and avoid autoimmunity (699 aa)
   
  0.992
HSP70
Probable mediator of RNA polymerase II transcription subunit 37c; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the [...] (650 aa)
     
  0.985
SQN
Peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in promoting the expression of the juvenile phase of vegetative development, and, to a lower extent, in regulating the positioning of floral buds, floral morphogenesis and the expression of HSPs (361 aa)
   
 
  0.970
ASY1
DNA-binding HORMA family protein; Required for normal meiosis in male and female gametophytes. Plays a crucial role in coordinating the activity of DMC1, a key member of the homologous recombination machinery. Acts at the interface between the developing chromosome axes and the recombination machinery to ensure DMC1- mediated interhomolog recombination (596 aa)
     
   
  0.967
AT5G58110
Chaperone binding;ATPase activators; Its function is described as ATPase activator activity, chaperone binding; Involved in biological_process unknown; Located in cytoplasm; Expressed in 23 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Activator of Hsp90 ATPase, N-terminal (InterPro-IPR015310); Has 297 Blast hits to 292 proteins in 99 species- Archae - 0; Bacteria - 0; Metazoa - 161; Fungi - 2; Plants - 78; Viruses - 0; Other Eukaryotes - 56 (source- NCBI BLink) (196 aa)
     
 
  0.960
AT3G12050
Uncharacterized protein T21B14.13; Aha1 domain-containing protein; Its function is described as ATPase activator activity, chaperone binding; Involved in response to stress; Located in cytoplasm; Expressed in 24 plant structures; Expressed during 16 growth stages; Contains the following InterPro domains- Activator of Hsp90 ATPase, N-terminal (InterPro-IPR015310), Activator of Hsp90 ATPase homologue 1-like (InterPro-IPR013538); Has 600 Blast hits to 579 proteins in 214 species- Archae - 0; Bacteria - 24; Metazoa - 217; Fungi - 180; Plants - 73; Viruses - 0; Other Eukaryotes - 106 (sourc [...] (360 aa)
     
 
  0.960
AT4G02450
HSP20-like chaperones superfamily protein; Its function is described as molecular_function unknown; Located in plasma membrane; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- CS-like domain (InterPro-IPR007052), HSP20-like chaperone (InterPro-IPR008978), CS domain (InterPro-IPR017447); BEST Arabidopsis thaliana protein match is- HSP20-like chaperones superfamily protein (TAIR-AT3G03773.1); Has 51861 Blast hits to 12232 proteins in 1049 species- Archae - 75; Bacteria - 28612; Metazoa - 10233; Fungi - 1929; Plants - 4069; Vir [...] (241 aa)
     
 
  0.953
AT3G03773
HSP20-like chaperones superfamily protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; Contains the following InterPro domains- CS-like domain (InterPro-IPR007052), HSP20-like chaperone (InterPro-IPR008978), CS domain (InterPro-IPR017447); BEST Arabidopsis thaliana protein match is- HSP20-like chaperones superfamily protein (TAIR-AT4G02450.2); Has 706 Blast hits to 706 proteins in 214 species- Archae - 0; Bacteria - 0; Metazoa - 339; Fungi - 125; Plants - 130; Viruses - 0; Other Eukaryotes - 112 (sourc [...] (204 aa)
     
 
  0.953
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (8%) [HD]