• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
OZS1 protein (Arabidopsis thaliana) - STRING interaction network
"OZS1" - C4-dicarboxylate transporter/malic acid transport protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OZS1C4-dicarboxylate transporter/malic acid transport protein; Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Cl(-) efflux through SLAC1 causes membrane depolarization, which activates outward- rectifying K1 channels, leading to KCl and water efflux to reduce turgor further and cause stomatal closure, that reduces water loss and promotes leaf turgor. Essential for stomatal closure in response to CO(2), abscisic acid (ABA), ozone O(3), light/dark transitions, humidity change, calcium ions, hydrogen peroxide H(2)O(2), reactive oxygen sp [...] (556 aa)    
Predicted Functional Partners:
OST1
Serine/threonine-protein kinase SRK2E; Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157-H7. As a plant defense process, stomata are closed transiently in order to limit invaders, bu [...] (362 aa)
       
 
  0.996
CPK6
Encodes calcium dependent protein kinase 6 (CPK6), a member of the Arabidopsis CDPK gene family. CDPKs contain an intrinsic Ca2+-activation domain with four EF hand Ca2+-binding sites. CDPKs protein kinases have been proposed to function in multiple plant signal transduction pathways downstream of [Ca2+]cyt elevations, thus transducing various physiological responses. CPK6 is expressed in both guard cells and mesophyll cells. Functions in guard cell ion channel regulation. ABA and Ca(2+) activation of slow-type anion channels and, interestingly, ABA activation of plasma membrane [...] (544 aa)
       
 
  0.972
CPK21
Calcium-dependent protein kinase 21; May play a role in signal transduction pathways that involve calcium as a second messenger. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1 (531 aa)
       
 
  0.958
CPK23
Calcium-dependent protein kinase 23; May play a role in signal transduction pathways that involve calcium as a second messenger. Could act as a calcium sensor involved in drought- and salt stress-induced calcium signaling cascades. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1 (533 aa)
       
 
  0.956
ALMT12
Aluminum-activated, malate transporter 12; Malate-sensitive anion transporter permeable to chloride, nitrate, sulfate and malate. Involved in dark-, CO(2)-, abscisic acid- and water-deficient-induced stomatal closure. Belongs to the R-type anion channels (560 aa)
     
   
  0.953
SNRK2.2
Serine/threonine-protein kinase SRK2D; Together with SRK2I, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure (369 aa)
       
 
  0.934
GHR1
Probable LRR receptor-like serine/threonine-protein kinase At4g20940; Leucine-rich receptor-like protein kinase family protein; Its function is described as protein serine/threonine kinase activity, protein kinase activity, ATP binding; Involved in signal transduction, N-terminal protein myristoylation; Located in plasma membrane; Contains the following InterPro domains- Serine/threonine-protein kinase domain (InterPro-IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro-IPR013210), Leucine-rich repeat (InterPro-IPR001611), Serine-threonine/tyrosine-protein ki [...] (977 aa)
           
  0.916
ABI1
Protein phosphatase 2C family protein; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseud [...] (434 aa)
           
  0.913
CDPK6
Encodes calcium dependent protein kinase 3 (CPK3), a member of the Arabidopsis CDPK gene family. CDPKs contain an intrinsic Ca2+-activation domain with four EF hand Ca2+-binding sites. CDPKs protein kinases have been proposed to function in multiple plant signal transduction pathways downstream of [Ca2+]cyt elevations, thus transducing various physiological responses. CPK3 is expressed in both guard cells and mesophyll cells. Functions in guard cell ion channel regulation. ABA and Ca(2+) activation of slow-type anion channels and, interestingly, ABA activation of plasma membrane [...] (529 aa)
       
 
  0.912
SNRK2.3
Sucrose nonfermenting 1(SNF1)-related protein kinase 2.3; Together with SRK2D, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (361 aa)
       
 
  0.910
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]