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CCS protein (Arabidopsis thaliana) - STRING interaction network
"CCS" - Copper chaperone for SOD1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CCSCopper chaperone for SOD1; Copper chaperone for the superoxide dismutases CSD1, CSD2 and CSD3. Binds copper ions and delivers them specifically to CSDs. Is required for assistance in CSDs disulfide bond formation and thereby activation of CSDs. May be involved in the negative regulation of heat stress-responsive genes and thermotolerance (320 aa)    
Predicted Functional Partners:
CSD2
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Mediates tolerance to stress, including photo-oxidative stress (216 aa)
     
 
0.992
CSD1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (152 aa)
     
 
0.990
CSD3
Copper/zinc superoxide dismutase 3; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (164 aa)
       
 
0.974
RAN1
RESPONSIVE-TO-ANTAGONIST 1; Involved in copper import into the cell. Essential for ethylene signaling, which requires copper. Acts by delivering copper to create functional hormone receptors (1001 aa)
     
  0.908
HMA8
P-type ATPase; Mediates copper transfer across the chloroplast thylakoid membrane. Required for copper delivery into the thylakoids lumen, which is essential for the function of copper proteins (883 aa)
     
  0.908
HMA1
Heavy metal atpase 1; Involved in cadmium/zinc transport (819 aa)
     
  0.908
HMA6
P-type ATP-ase 1; Mediates copper transfer across the plastid envelope. Required for the delivery of copper into the plastid stroma, which is essential for the function of copper proteins. Seems to be selective for monovalent copper Cu(+) transport. Plays also a role in glucose signaling-mediated cell proliferation of root meristem in non-green tissues (949 aa)
     
  0.908
HMA3
Heavy metal atpase 3 (542 aa)
     
  0.908
HMA2
Heavy metal atpase 2; Plays an important role in zinc transport and homeostasis. Could also be involved in cadmium detoxification (951 aa)
     
  0.908
HMA4
Heavy metal atpase 4; Involved in cadmium/zinc transport (1172 aa)
     
  0.908
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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