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AT1G12530 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G12530" - Uncharacterized protein in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G12530Uncharacterized protein (193 aa)    
Predicted Functional Partners:
SDG25
SET domain protein 25; Histone methyltransferase involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS-box genes of the MAF family (PubMed-19726574, PubMed-19855050). Required for histone H3 dimethylation on ’Lys-36’ H3K36me2 at the FLC locus (PubMed-19726574). Required for histone H3 trimethylation on ’Lys- 4’ H3K4me3 at the FLC locus. Prevents trimethylation on ’Lys-27’ H3K276me3 at the same locus (PubMed-19855050). Involved in the control of seed dormancy and germination (PubMed-21799800) (1423 aa)
       
 
  0.855
SDG37
SET domain group 37; Histone methyltransferase (480 aa)
           
  0.670
MOS1
MODIFIER OF snc1; Involved in the regulation of the chromatin structure and DNA methylation at the SNC1 locus. Regulates the expression of SNC1 at chromatin level (1427 aa)
           
  0.598
AT1G09200
Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (136 aa)
       
      0.578
HCF173
High chlorophyll fluorescence phenotype 173 (598 aa)
       
      0.578
SRT2
Sirtuin 2; NAD-dependent protein deacylase. Catalyzes the NAD- dependent hydrolysis of acyl groups from lysine residues (By similarity). Negatively regulates plant basal defense against plant pathogens, possibly by suppressing salicylic acid biosynthesis (376 aa)
           
  0.504
RPP4
Recognition of peronospora parasitica 4; TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis isolates Emoy2 and Emwa1 (downy mildew disease) (PubMed-11846877). Plays a role in the regulation of temperature response during plant growth and survival (PubMed-20699401) (1147 aa)
           
  0.493
LAZ5
LAZARUS 5; TIR-NB-LRR receptor-like protein that may play a role in plant innate immunity. May trigger hypersensitive programmed cell death in response to pathogen attack (PubMed-20949080). Involved in tolerance to tobacco ringspot virus (TRSV) (PubMed-22057987) (1170 aa)
           
  0.475
SET27
Homologue of trithorax; Histone methyltransferase. Methylates ’Lys-4’ of histone H3. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. Required to maintain the active state of class A (AP1 and AP2), class B (PI and AP3) and class C (AG) floral homeotic genes at early stages of flower development. Regulates floral organ identity and flowering transition. Functions as a receptor for the lipid messenger phosphatidylinositol 5-phosphate (PI5P), which regulates negatively its transcriptional activation activity (1062 aa)
           
  0.474
HUB2
Histone mono-ubiquitination 2; E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6 (900 aa)
           
  0.449
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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