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AT1G12540 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G12540" - Basic helix-loop-helix in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AT1G12540Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Its function is described as DNA binding, sequence-specific DNA binding transcription factor activity; Involved in regulation of transcription; Located in nucleus; Contains the following InterPro domains- Helix-loop-helix DNA-binding domain (InterPro-IPR001092), Helix-loop-helix DNA-binding (InterPro-IPR011598); BEST Arabidopsis thaliana protein match is- basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR-AT1G62975.1); Has 394 Blast hits to 394 proteins in 30 species- Archae - 0; Bacteria - 0; Metazoa - 5; [...] (257 aa)    
Predicted Functional Partners:
AT1G24600
At1g24600; Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT1G67920.1); Has 18 Blast hits to 18 proteins in 5 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 18; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (72 aa)
           
  0.951
CYP79F1
Dihomomethionine N-hydroxylase; Catalyzes the conversion of the short chain elongated methionines di-, tri-, and tetrahomomethionine to their respective aldoximes 5-methylthiopentanaldoxime, 6-methylthiohexanaldoxime, and 7-methylheptanaldoxime (538 aa)
           
  0.623
AT1G66260
RNA-binding (RRM/RBD/RNP motifs) family protein; Export adapter involved in nuclear export of spliced and unspliced mRNA (295 aa)
           
  0.610
AT1G78820
D-mannose binding lectin protein with Apple-like carbohydrate-binding domain; Its function is described as sugar binding; Located in apoplast; Contains the following InterPro domains- Curculin-like (mannose-binding) lectin (InterPro-IPR001480), PAN-2 domain (InterPro-IPR013227), Apple-like (InterPro-IPR003609); BEST Arabidopsis thaliana protein match is- Curculin-like (mannose-binding) lectin family protein (TAIR-AT1G78830.1); Has 2616 Blast hits to 2560 proteins in 84 species- Archae - 0; Bacteria - 5; Metazoa - 0; Fungi - 0; Plants - 2610; Viruses - 0; Other Eukaryotes - 1 (source- N [...] (455 aa)
           
  0.565
KAT3
Encodes KAT3, a member of the Shaker family of voltage-gated potassium channel subunits. Does not form functional potassium channel on its own. Involved in down-regulating AKT1 and KAT1 channel activity by forming heteromers with AKT1 or KAT1. The Shaker family K+ ion channels include five groups based on phylogenetic analysis (FEBS Letters (2007) 581- 2357)- I (inwardly rectifying conductance)- AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel)- KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel)- AKT2 [...] (662 aa)
           
  0.553
AT1G15370
Uncharacterized protein At1g15370/F9L1_32; SNARE-like superfamily protein; Its function is described as molecular_function unknown; Involved in transport; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Longin-like (InterPro-IPR011012); Has 91 Blast hits to 91 proteins in 35 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 12; Plants - 67; Viruses - 0; Other Eukaryotes - 12 (source- NCBI BLink) (147 aa)
           
  0.553
FBH3
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Its function is described as DNA binding, sequence-specific DNA binding transcription factor activity; Involved in regulation of transcription; Located in nucleus; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Helix-loop-helix DNA-binding domain (InterPro-IPR001092), Helix-loop-helix DNA-binding (InterPro-IPR011598); BEST Arabidopsis thaliana protein match is- basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR-AT2G42280.1); Has 1835 Blast hits [...] (379 aa)
           
  0.532
ATMYC1
MYC-related protein with a basic helix-loop-helix motif at the C-terminus and a region similar to the maize B/R family at the N-terminus (580 aa)
           
  0.530
AT2G14800
Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT3G44713.1); Has 41 Blast hits to 38 proteins in 14 species- Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 2; Plants - 16; Viruses - 0; Other Eukaryotes - 16 (source- NCBI BLink) (620 aa)
           
  0.530
KT2/3
Potassium channel AKT2/3; Encodes AKT2, a photosynthate- and light-dependent inward rectifying potassium channel with unique gating properties that are regulated by phosphorylation. Expressed in guard cell protoplasts and in the phloem and xylem of aerial portions of the plant. The channel can coassemble with another K+ channel, KAT1, in vitro. In guard cells, AKT2/3 is responsible for the Ca2+ sensitivity of the K+ uptake channel. In the phloem, it regulates the sucrose/H+ symporters via the phloem potential. AKT2 belongs to the Shaker family K+ channels which include the followi [...] (802 aa)
           
  0.529
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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