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SCRM2 protein (Arabidopsis thaliana) - STRING interaction network
"SCRM2" - Basic helix-loop-helix in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
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Gene Fusion
SCRM2Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Encodes ICE2 (Inducer of CBF Expression 2), a transcription factor of the bHLH family that participates in the response to deep freezing through the cold acclimation-dependent pathway. Overexpression of ICE2 results in increased tolerance to deep freezing stress after cold acclimation (450 aa)    
Predicted Functional Partners:
Encodes a basic helix-loop-helix (bHLH) transcription factor that is necessary and sufficient for the asymmetric divisions that establish the stomatal lineage in Arabidopsis thaliana. Expression of SPCH in young epidermal cells allows these cells to make asymmetric divisions. SPCH is a substrate of a kinase MPK3 and MPK6 (364 aa)
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata (202 aa)
Leucine-rich repeat (LRR) family protein; Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC). Modulates probably the activity of the ligand- receptor pairs EPF2-ERECTA and EPF1-ERL1 via heterodimerization (496 aa)
E3 ubiquitin-protein ligase HOS1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways. Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels (927 aa)
LRR receptor-like serine/threonine-protein kinase ERL2; Encodes a receptor-like kinase that, together with ER and ERL1 governs the initial decision of protodermal cells to either divide proliferatively to produce pavement cells or divide asymmetrically to generate stomatal complexes. It is also important for maintaining stomatal stem cell activity and preventing terminal differentiation of the meristemoid into the guard mother cell. When heterozygous in an er/erl1 null background, plants are female sterile due to cell division defect in the integuments (967 aa)
Protein EPIDERMAL PATTERNING FACTOR 1; Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1). MEPF1- mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERL1 as major receptor. May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1); Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily (104 aa)
Unknown protein; Located in chloroplast; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT3G59870.1); Has 292 Blast hits to 292 proteins in 84 species- Archae - 0; Bacteria - 122; Metazoa - 0; Fungi - 0; Plants - 46; Viruses - 0; Other Eukaryotes - 124 (source- NCBI BLink) (289 aa)
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Transcription activator. Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity. Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata. Prevents histone H3K27me3 marks and derepresses stem cell gene expression (414 aa)
Uncharacterized protein F24G16.140; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in chloroplast; Expressed in 23 plant structures; Expressed during 13 growth stages; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT2G43945.1); Has 292 Blast hits to 292 proteins in 84 species- Archae - 0; Bacteria - 122; Metazoa - 0; Fungi - 0; Plants - 46; Viruses - 0; Other Eukaryotes - 124 (source- NCBI BLink) (288 aa)
Jasmonate-zim-domain protein 4; Repressor of jasmonate responses; Belongs to the TIFY/JAZ family (310 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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