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PIRL3 protein (Arabidopsis thaliana) - STRING interaction network
"PIRL3" - Encodes PIRL3, a member of the Plant Intracellular Ras-group-related LRRs (Leucine rich repeat proteins). PIRLs are a distinct, plant-specific class of intracellular LRRs that likely mediate protein interactions, possibly in the context of signal transduction in Arabidopsis thaliana
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PIRL3Encodes PIRL3, a member of the Plant Intracellular Ras-group-related LRRs (Leucine rich repeat proteins). PIRLs are a distinct, plant-specific class of intracellular LRRs that likely mediate protein interactions, possibly in the context of signal transduction (464 aa)    
Predicted Functional Partners:
ROPGEF11
Rop guanine nucleotide exchange factor 11; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Functions as a light-signaling switch that functions in root growth and development through the activation of Rop in a phytochrome-dependent manner. May act as a negative regulator of phytochrome-mediated primary root development (607 aa)
       
 
  0.860
AAE1
Probable acyl-activating enzyme 1, peroxisomal; May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs; Belongs to the ATP-dependent AMP-binding enzyme family (556 aa)
           
  0.838
AT2G19340
Oligosaccharyltransferase complex/magnesium transporter family protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in plasma membrane; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Oligosaccharyltransferase complex/magnesium transporter (InterPro-IPR021149); BEST Arabidopsis thaliana protein match is- Oligosaccharyltransferase complex/magnesium transporter family protein (TAIR-AT4G29870.1); Has 214 Blast hits to 214 proteins in 79 species- Archae - 0; Bacteria - [...] (200 aa)
           
  0.837
AT5G13780
N-terminal acetyltransferase A complex catalytic subunit NAA10; Catalytic subunit of the NatA N-alpha-acetyltransferase complex. Required for male gametocyte development, embryogenesis, suspensor development and the formation of the quiescent center (QC) in the root meristem. Involved in plant immunity through the regulation of SNC1 and RPM1 stability (192 aa)
           
  0.810
TSC10A
NAD(P)-binding Rossmann-fold superfamily protein; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Lacks stereospecificity and can also produce L-threo-DHS in addition to D-erythro-DHS; Belongs to the short-chain dehydrogenases/reductases (SDR) family (326 aa)
           
  0.758
LON2
Lon protease homolog 2, peroxisomal; Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins (888 aa)
       
 
  0.699
CYP72A13
Cytochrome P450, family 72, subfamily A, polypeptide 13; Putative cytochrome P450 (512 aa)
           
  0.699
AAE3
AMP-dependent synthetase and ligase family protein; Oxalyl-CoA synthetase acting exclusively against oxalate. No activity with malonate, succinate, malate, acetate, formate, lactate, glycolate, glyoxylate or glutarate. Required for oxalate degradation, normal seed development and defense against oxalate-producing fungal pathogens (514 aa)
           
  0.693
MSL3
Mechanosensitive ion channel protein 3, chloroplastic; A member of MscS-like gene family, structurally very similar to MSL2, comprising of an N-terminal chloroplast transit peptide, five trans-membrane helices and a C-terminal cytoplasmic domain. Mutant plants showed abnormalities in the size and shape of plastids. MSL3-GFP was localized to discrete foci on the plastid envelope and co-localize with the plastid division protein AtMinE. MSL3 was capable of increasing the osmotic-shock survival of a mutant bacterial strain lacking MS-ion-channel activity; Belongs to the MscS (TC 1.A.23) family (678 aa)
           
  0.646
ERD7
Protein EARLY-RESPONSIVE TO DEHYDRATION 7, chloroplastic; Identified as drought-inducible gene by differential hybridization. Upregulated by high light, drought, cold and salt stress determined by microarray analysis (452 aa)
           
  0.624
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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