STRINGSTRING
LINC2 protein (Arabidopsis thaliana) - STRING interaction network
"LINC2" - LITTLE NUCLEI2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LINC2LITTLE NUCLEI2; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (By similarity). Required for nucleus structure organization (e.g. size and shape) (PubMed-17873096, PubMed-24308514, PubMed-23396599) (1128 aa)    
Predicted Functional Partners:
NUP1
Uncharacterized protein; Nucleoporin required for nuclear mRNA export. Functions as an adapter and/or regulator molecule in the periphery of the nuclear pore complex (NPC). May interact with importin proteins and mediate active nucleocytoplasmic transport through the NPC. Involved in regulation of nuclear morphology (1309 aa)
           
  0.811
SUN1
SAD1/UNC-84 domain protein 1; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed-24667841). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed-21294795). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed-22270916) (471 aa)
           
  0.810
AT3G44380
Late embryogenesis abundant hydroxyproline-rich glycoprotein (186 aa)
           
  0.809
NUA
Nucleoprotein TPR; Component of the nuclear pore complex. Acts as a docking site for activities required for desumoylation and mRNA export. Required for the proper expression or localization of a subset of miRNAs. Plays a role in meristematic cell division by interacting with spindle assembly checkpoint proteins (2115 aa)
     
   
  0.759
ENODL16
Early nodulin-like protein 16 (167 aa)
           
  0.748
AT1G73240
Uncharacterized protein (519 aa)
           
  0.748
WIP1
WPP domain interacting protein 1; Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (489 aa)
     
   
  0.746
SUN2
SAD1/UNC-84 domain protein 2; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed-24667841). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed-21294795). Modulates the anchoring and mobility of WIP proteins in the nuclear envelope (NE) (PubMed-22270916) (455 aa)
           
  0.739
WIT1
WPP domain-interacting protein 1; Together with WIT2, required for the nuclear envelope docking of RANGAP proteins in root tips (703 aa)
     
   
  0.689
AT4G31430
Uncharacterized protein; Required for nucleus structure organization (e.g. size and shape) (574 aa)
           
  0.654
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (13%) [HD]