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DOT5 protein (Arabidopsis thaliana) - STRING interaction network
"DOT5" - C2H2-like zinc finger protein in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOT5C2H2-like zinc finger protein; Probable transcriptional regulator (Probable). Involved in leaf vasculature patterning (PubMed-18643975) (302 aa)    
Predicted Functional Partners:
AT2G20050
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein (1094 aa)
     
  0.971
BRL1
BRI1 like; Receptor with a serine/threonine-protein kinase activity. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. Binds brassinolide. May be involved in cell growth and vascular differentiation (1166 aa)
     
  0.775
AT3G11830
TCP-1/cpn60 chaperonin family protein; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (557 aa)
       
 
  0.746
AT3G13350
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (319 aa)
       
  0.742
AT1G76110
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (PubMed-19053246). Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed-16698901) (338 aa)
       
  0.742
AT1G55650
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (337 aa)
       
  0.742
AT1G04880
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (448 aa)
       
  0.742
TSA2
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate. Required for tryptophan biosynthesis. Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production (312 aa)
           
  0.740
AT2G40860
Putative protein phosphatase 2C 31 (658 aa)
     
  0.710
ERL2
ERECTA-like 2; Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ERL1 and ER (967 aa)
     
  0.707
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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