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NUB protein (Arabidopsis thaliana) - STRING interaction network
NUBBIN in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NUBNUBBIN; Acts with JAG to promote growth and patterning in stamens and carpels. Promotes the growth of the abaxial and adaxial sides of floral organs. Promotes the growth of the pollen- bearing microsporangia in anthers, the carpel walls of the gynoecium and the establishment of the correct number of cell layers in carpel walls. Promotes leaf blade growth and trichome development (207 aa)    
Predicted Functional Partners:
AFO
ABNORMAL FLORAL ORGANS; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development (PubMed-10323860, PubMed-10331982, PubMed-10457020, PubMed-11812777, PubMed-12417699, PubMed-9878633, Ref.3, Ref.6, PubMed-19837869). Required during flower formation and development, particularly for the patterning of floral organs. Positive regulator of class B (AP3 and PI) activity in whorls 2 and 3. Negative regulator of class B activity in whorl 1 and of SUP activity in whorl 3. Interacts with [...] (229 aa)
     
   
  0.643
BOP1
BLADE ON PETIOLE 1; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co- regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB [...] (467 aa)
           
  0.600
STE14A
Homolog of yeast STE14 A; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues, resulting in the modulation of the function of prenylated proteins. Involved in negative regulation of abscisic acid signaling. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins (197 aa)
           
  0.553
HCF153
High chlorophyll fluorescence 153 (137 aa)
           
  0.553
ANT
AINTEGUMENTA; Transcription activator that recognizes and binds to the DNA consensus sequence 5’-CAC[AG]N[AT]TNCCNANG-3’. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regul [...] (555 aa)
     
   
  0.532
YAB3
YABBY3; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development (PubMed-10457020, PubMed-12417699, PubMed-19837869). Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems. Binds DNA without sequence specificity (PubMed-10457020, PubMed-12417699) (240 aa)
           
  0.491
BOP2
BLADE ON PETIOLE2; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co- regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB1 [...] (491 aa)
           
  0.489
PAN
PERIANTHIA; Transcriptional activator involved in the determination of floral organ number. Acts to determine floral organ patterning by establishing floral organ primordia in specific numbers and positions. Plays a role in regulating stem cell fate by directly controlling AG expression. Binds to the 5’-AAGAAT-3’ cis-acting element found in AG promoter. Might represent a target for a post- translational modification by GRXC7/ROXY1 (452 aa)
     
   
  0.490
AS2
ASYMMETRIC LEAVES 2; Negative regulator of cell proliferation in the adaxial side of leaves. Regulates the formation of a symmetric lamina and the establishment of venation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 1 (AS1) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (P [...] (199 aa)
           
  0.478
ZAT6
Zinc finger of Arabidopsis thaliana 6; Probable transcription factor that regulates root development and phosphate (Pi) acquisition and homeostasis. Probably acts as a repressor of primary root growth and regulates Pi homeostasis through the control of root architecture (238 aa)
           
  0.474
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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