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WHY1 protein (Arabidopsis thaliana) - STRING interaction network
"WHY1" - WHIRLY 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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WHY1WHIRLY 1; Single-stranded DNA-binding protein that functions in both chloroplasts and nucleus. In chloroplasts, maintains plastid genome stability by preventing break-induced and short homology- dependent illegitimate recombinations. In nucleus, modulates telomere length homeostasis by inhibiting the action of the telomerase at the extreme termini of chromosomes. Is recruited to a distal element upstream of the kinesin KP1 to mediate the transcriptional repression of KP1. Is required for full salicylic acid-dependent plant disease resistance responses. Can bind double-stranded DNA in vivo (263 aa)    
Predicted Functional Partners:
CITRX
Thioredoxin z; Thiol-disulfide oxidoreductase that plays a role in proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription. Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression. May be involved in cell death and defense responses (By similarity) (183 aa)
     
   
  0.806
PTAC2
Plastid transcriptionally active 2; Involved in plastid gene expression (862 aa)
     
   
  0.764
FSD3
Fe superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (By similarity). Plays important role in chloroplast development, particularly in the maintenance of thylakoids membranes. Seems to act as a heterodimer with FSD2 (263 aa)
     
   
  0.760
MSH1
MUTL protein homolog 1; DNA mismatch repair protein specifically involved in maintenance of mitochondrial genome configuration by controlling specific rearranged portion. Functions by suppressing asymmetric recombination at some repeat pairs (1118 aa)
     
   
  0.757
FLN1
Fructokinase-like 1; Required for proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription. Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression (471 aa)
     
   
  0.751
PTAC12
Plastid transcriptionally active 12; Involved in plastid gene expression (PubMed-16326926). Required in the nucleus for the initiation of photomorphogenesis mediated by phytochromes (PHYs) (e.g. PHYA and PHYB) by mediating PHYs localization to photobodies, especially in response to red and far-red light, and implicating phytochrome nuclear bodies as sites of proteolysis for PHYs and PIFs proteins (e.g. PIF1 and PIF3). Acts downstream of PHYs and upstream of DET1 (PubMed-20603003, PubMed-22895253) (527 aa)
     
   
  0.731
PRIN2
Uncharacterized protein (179 aa)
     
   
  0.729
FLN2
Fructokinase-like 2; Required for proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription. Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression (616 aa)
     
   
  0.725
MRL7
Uncharacterized protein (331 aa)
     
   
  0.723
PTAC14
Plastid transcriptionally active 14; Essential for chloroplast development, especially for thylakoid formation. Involved in plastid gene expression, probably by maintaining plastid-encoded RNA polymerase (PEP) activity (483 aa)
     
   
  0.716
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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