STRINGSTRING
AL7 protein (Arabidopsis thaliana) - STRING interaction network
"AL7" - Alfin-like 7 in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AL7Alfin-like 7; Histone-binding component that specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes (252 aa)    
Predicted Functional Partners:
TRO
TRAUCO; Trithorax-group gene homolog required for early embryogenesis (PubMed-20118203, PubMed-21423667). Required for the expression of FLC and FLC homologs and represses flowering (PubMed-21423667). Required for proper leaf growth and development (PubMed-21423667). Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 ’Lys-4’ (PubMed-21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed-21423667) (509 aa)
     
 
  0.950
AT3G21060
RbBP5 LIKE; Promotes the expression of FLC and FLC homologs to repress the floral transition (547 aa)
       
 
  0.948
AT2G31130
Uncharacterized protein (419 aa)
           
  0.863
RING1A
RING 1A (525 aa)
     
 
  0.851
AT5G66240
transducin/WD40 domain-containing protein (331 aa)
     
 
  0.827
SDG2
SET domain protein 2; Histone methyltransferase specifically required for trimethylation of ’Lys-4’ of histone H3 (H3K4me3) and is crucial for both sporophyte and gametophyte development (PubMed-21037105, PubMed-20937886) (2335 aa)
     
 
  0.825
ATX2
Trithorax-like protein 2; Histone methyltransferase (1083 aa)
     
 
  0.824
AT5G14530
transducin/WD40 domain-containing protein (330 aa)
       
 
  0.823
SDG16
SET domain protein 16; Histone methyltransferase (1027 aa)
     
 
  0.823
SDG29
SET domain group 29; Histone methyltransferase (1043 aa)
     
 
  0.818
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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