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STRINGSTRING
AT1G14688 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G14688" - E3 ubiquitin ligase in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AT1G14688E3 ubiquitin ligase; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in cellular_component unknown; Contains the following InterPro domains- E3 Ubiquitin ligase (InterPro-IPR022170); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (170 aa)    
Predicted Functional Partners:
MCM4
Minichromosome maintenance (MCM2/3/5) family protein; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (847 aa)
     
   
  0.921
EMB2656
ARM repeat superfamily protein; EMBRYO DEFECTIVE 2656 (EMB2656); Its function is described as binding; Involved in mitotic chromosome condensation, embryo development ending in seed dormancy; Located in cellular_component unknown; Expressed in 11 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Armadillo-type fold (InterPro-IPR016024); Has 333 Blast hits to 316 proteins in 147 species- Archae - 0; Bacteria - 4; Metazoa - 113; Fungi - 138; Plants - 47; Viruses - 0; Other Eukaryotes - 31 (source- NCBI BLink) (1051 aa)
     
   
  0.915
AT4G21820
Binding;calmodulin binding; Its function is described as calmodulin binding, binding; Located in chloroplast; Expressed in 13 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Calponin-homology (InterPro-IPR016146), Armadillo (InterPro-IPR000225), Calponin-like actin-binding (InterPro-IPR001715), Armadillo-type fold (InterPro-IPR016024), IQ calmodulin-binding region (InterPro-IPR000048); BEST Arabidopsis thaliana protein match is- myosin 2 (TAIR-AT5G43900.1); Has 3955 Blast hits to 2210 proteins in 242 species- Archae - 0; Bacteria - 4; Metazo [...] (1255 aa)
     
   
  0.911
PPK1
Uncharacterized protein At1g77720; Encodes a predicted protein kinase based on sequence similarity (777 aa)
     
 
  0.911
MAD2
Mitotic spindle checkpoint protein MAD2; Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate (209 aa)
     
 
  0.909
THY-2
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (565 aa)
     
   
  0.903
AT2G21550
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (492 aa)
     
   
  0.903
THY-1
Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (519 aa)
     
   
  0.903
AT3G54630
Uncharacterized protein T14E10_200; Contains the following InterPro domains- Kinetochore protein Ndc80 (InterPro-IPR005550); Has 24780 Blast hits to 15608 proteins in 1321 species- Archae - 545; Bacteria - 2969; Metazoa - 12597; Fungi - 2181; Plants - 1581; Viruses - 39; Other Eukaryotes - 4868 (source- NCBI BLink) (568 aa)
     
   
  0.901
MCM5
Minichromosome maintenance (MCM2/3/5) family protein; Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin (727 aa)
     
   
  0.900
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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