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AT1G15970 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G15970" - DNA glycosylase superfamily protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G15970DNA glycosylase superfamily protein; Its function is described as DNA-3-methyladenine glycosylase I activity, catalytic activity; Involved in DNA repair, base-excision repair; Located in cellular_component unknown; Contains the following InterPro domains- DNA glycosylase (InterPro-IPR011257), Methyladenine glycosylase (InterPro-IPR005019); BEST Arabidopsis thaliana protein match is- DNA glycosylase superfamily protein (TAIR-AT1G80850.1); Has 3684 Blast hits to 3684 proteins in 1581 species- Archae - 10; Bacteria - 3170; Metazoa - 10; Fungi - 2; Plants - 164; Viruses - 0; Other Eukaryot [...] (352 aa)    
Predicted Functional Partners:
AT1G75230
DNA glycosylase superfamily protein; Its function is described as catalytic activity; Involved in DNA repair, base-excision repair; Located in nucleus; Expressed in 18 plant structures; Expressed during 9 growth stages; Contains the following InterPro domains- DNA glycosylase (InterPro-IPR011257), HhH-GPD domain (InterPro-IPR003265); BEST Arabidopsis thaliana protein match is- DNA glycosylase superfamily protein (TAIR-AT1G19480.1); Has 35333 Blast hits to 34131 proteins in 2444 species- Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryo [...] (394 aa)
         
  0.917
AT1G19480
DNA glycosylase superfamily protein; Its function is described as catalytic activity; Involved in DNA repair, base-excision repair; Located in chloroplast; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- DNA glycosylase (InterPro-IPR011257), HhH-GPD domain (InterPro-IPR003265); BEST Arabidopsis thaliana protein match is- DNA glycosylase superfamily protein (TAIR-AT1G75230.1); Has 4603 Blast hits to 4603 proteins in 1096 species- Archae - 62; Bacteria - 2357; Metazoa - 1; Fungi - 142; Plants - 80; Viruses - 0; Other Eukaryote [...] (382 aa)
         
  0.917
AT3G50880
Putative DNA-3-methyladenine glycosidase; DNA glycosylase superfamily protein; Its function is described as catalytic activity; Involved in DNA repair, base-excision repair; Located in chloroplast; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- DNA glycosylase (InterPro-IPR011257), HhH-GPD domain (InterPro-IPR003265); BEST Arabidopsis thaliana protein match is- DNA glycosylase superfamily protein (TAIR-AT1G19480.2); Has 4313 Blast hits to 4311 proteins in 953 species- Archae - 62; Bacteria - 2052; Metazoa - 1; Fungi - 144; [...] (273 aa)
         
  0.878
NTH2
Endonuclease III homolog 2, chloroplastic; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family (386 aa)
           
  0.863
ATNTH1
Endonuclease III homolog 1, chloroplastic; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines (379 aa)
           
  0.769
HMGB5
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Cannot be phosphorylated by CK2alpha (125 aa)
           
  0.699
DML2
DEMETER-like protein 2; Potential transcriptional activator that may act by nicking the target promoter. Catalyzes the release of 5- methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism (By similarity) (1332 aa)
           
  0.635
HMGB1
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha. In interphase cells, HMGB1 is found throughout the nucleus, whereas in mitotic cells it is not chromatin-associated (185 aa)
           
  0.600
DML3
DEMETER-like protein 3; Potential transcriptional activator that may act by nicking the target promoter. Catalyzes the release of 5- methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism (By similarity) (1044 aa)
           
  0.588
AT3G01660
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Its function is described as methyltransferase activity; Involved in metabolic process; Located in cellular_component unknown; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Methyltransferase type 11 (InterPro-IPR013216); BEST Arabidopsis thaliana protein match is- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR-AT4G29590.1); Has 1347 Blast hits to 1347 proteins in 403 species- Archae - 26; Bacteria - 759; Metazoa - 25; [...] (273 aa)
           
  0.582
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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