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AT1G16800 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G16800" - P-loop containing nucleoside triphosphate hydrolases superfamily protein in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AT1G16800P-loop containing nucleoside triphosphate hydrolases superfamily protein; BEST Arabidopsis thaliana protein match is- P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR-AT4G30100.1); Has 9771 Blast hits to 8579 proteins in 1344 species- Archae - 197; Bacteria - 2032; Metazoa - 2727; Fungi - 1277; Plants - 815; Viruses - 364; Other Eukaryotes - 2359 (source- NCBI BLink) (2127 aa)    
Predicted Functional Partners:
tRNA-splicing endonuclease subunit Sen2-1; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (237 aa)
Cell division cycle 5-like protein; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage; Belongs to the CEF1 family (844 aa)
Sister chromatid cohesion protein SCC2; Essential protein required for cell fate determination during embryogenesis. Involved in sister chromatid cohesion during meiosis and mitosis. Forms a complex with SCC4, which is required for the association of the cohesin complex with chromosomes. Plays a structural role in chromatin, especially in centromere organization, chromosomal axis formation, and distribution of the cohesin subunit SCC3 on chromosomes (1846 aa)
Uncharacterized protein At2g02880/T17M13.5; Mucin-related; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT5G62270.1); Has 128 Blast hits to 128 proteins in 36 species- Archae - 0; Bacteria - 3; Metazoa - 3; Fungi - 6; Plants - 91; Viruses - 0; Other Eukaryotes - 25 (source- NCBI BLink) (314 aa)
Regulator of nonsense transcripts UPF2; Recruited by UPF3 associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Required for plant develo [...] (1181 aa)
Protein transport protein SEC16B homolog; Required for protein transport from the endoplasmic reticulum to the Golgi apparatus (1361 aa)
Protein transport protein SEC16A homolog; Required for efficient protein export from the endoplasmic reticulum (ER) to the Golgi by regulating COPII coat dynamics at the ER. Functions as a scaffold and regulator of COPII coat assembly at ER exit sites; Belongs to the SEC16 family (1350 aa)
E3 ubiquitin-protein ligase PRT6; Ubiquitin ligase protein which is a component of the N- end rule pathway with the arginyltransferases ATE1 and ATE2. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Does not participate in degradation of proteins with N-terminal Phe or Leu. The N-end rule pathway regulates seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination. The end-rule pathway re [...] (2006 aa)
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with t [...] (257 aa)
Transcription factor bHLH140; Encodes a protein that has adenylylsulfate sulfohydrolase activity (E.C. in vitro (912 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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