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STRINGSTRING
SHA protein (Arabidopsis thaliana) - STRING interaction network
"SHA" - Encodes a protein that contains an SH2 domain. It can pull down a 120-kD tyrosine-phosphorylated protein in vitro. It is predicted to act as a transcription factor in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SHAEncodes a protein that contains an SH2 domain. It can pull down a 120-kD tyrosine-phosphorylated protein in vitro. It is predicted to act as a transcription factor (651 aa)    
Predicted Functional Partners:
AT1G53815
F-box family protein; Contains the following InterPro domains- F-box domain, cyclin-like (InterPro-IPR001810), F-box domain, Skp2-like (InterPro-IPR022364); BEST Arabidopsis thaliana protein match is- F-box family protein (TAIR-AT1G53550.1); Has 35333 Blast hits to 34131 proteins in 2444 species- Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source- NCBI BLink) (237 aa)
           
  0.792
HAM4
GRAS family transcription factor; Probable transcription factor involved in plant development; Belongs to the GRAS family (486 aa)
           
  0.612
XTH32
Probable xyloglucan endotransglucosylase/hydrolase protein 32; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity) (299 aa)
           
  0.569
SQN
Peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in promoting the expression of the juvenile phase of vegetative development, and, to a lower extent, in regulating the positioning of floral buds, floral morphogenesis and the expression of HSPs (361 aa)
           
  0.553
IKU2
Leucine-rich repeat protein kinase family protein; Encodes leucine rich repeat (LRR) kinase. Iku2-3 identified in a screen for mutants with abnormal endosperm. Sporophytic recessive mutants have reduced embryo and endosperm size. Seed size is also reduced and the shape is abnormal suggesting an interaction between the endosperm and cell elongation in the integuments; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (991 aa)
           
  0.546
MLO7
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO7 belongs to the clade III, with AtMLO5, AtMLO8, AtMLO9, and AtMLO10. The gene is expressed in vegetative organs (RT-PCR experiments)and in pollen grains, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes [...] (542 aa)
           
  0.524
AT1G69170
Squamosa promoter-binding protein-like (SBP domain) transcription factor family protein; Trans-acting factor that binds specifically to the consensus nucleotide sequence 5’-TNCGTACAA-3’ (405 aa)
           
  0.471
RD21A
Granulin repeat cysteine protease family protein; Cysteine protease that plays a role in immunity, senescence, and biotic and abiotic stresses (Probable). Involved in immunity against the necrotrophic fungal pathogen Botrytis cinerea. Involved in elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions as PCD-promoting protease that is released from the ER body or vacuole to the cytoplasm. Accumulates in endoplasmic reticulum- derived bodies in epidermal cells and may participate in cell death in stressed or injur [...] (462 aa)
           
  0.463
TCP2
TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2; Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary- specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule develpment. Participates in ovule develpment. Promotes light-regulated transcription of CHS, CAB, HYH and HY5. Regulates positively photomorphogenesis (e.g. hypocotyl elongation inhibition and cotyledon opening in response to blue light) (365 aa)
           
  0.450
THI2.2
Thionin-2.2; Encodes a thionin that is expressed at a low basal level in seedlings and shows circadian variation. Predicted to encode a PR (pathogenesis-related) protein. Belongs to the plant thionin (PR-13) family with the following members- At1g66100, At5g36910, At1g72260, At2g15010, At1g12663, At1g12660 (134 aa)
           
  0.414
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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