STRINGSTRING
SPS2 protein (Arabidopsis thaliana) - STRING interaction network
"SPS2" - Solanesyl diphosphate synthase 2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPS2Solanesyl diphosphate synthase 2; Involved in providing solanesyl diphosphate for plastoquinone-9 formation. Prefers geranylgeranyl diphosphate to farnesyl diphosphate as substrate. No activity with geranyl diphosphate or dimethylallyl diphosphate as substrate (417 aa)    
Predicted Functional Partners:
PPT1
Polyprenyltransferase 1 (429 aa)
   
 
  0.988
At3g11945
Homogentisate prenyltransferase (393 aa)
   
 
  0.987
SPS1
Solanesyl diphosphate synthase 1; Involved in the solanesyl diphosphate biosynthesis in the endoplasmic reticulum. This isoprenoid side chain might be then transferred to the mitochondria for the synthesis of ubiquinone-9. Prefers geranylgeranyl diphosphate to farnesyl diphosphate as substrate. No activity with geranyl diphosphate or dimethylallyl diphosphate as substrate (406 aa)
   
 
0.983
HPT1
Homogentisate phytyltransferase 1; Involved in the synthesis of tocopherol (vitamin E). Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydrquinone. Low activity with geranylgeranyl diphosphate as substrate, but no activity with farnesyl diphosphate or solanesyl diphosphate. Tocopherol functions to limit lipid oxidation during seed desiccation, quiescence and germination and early seedling development. Protects thylakoid membrane lipids from photooxidation and is required for low-temperature adaptation (393 aa)
   
 
  0.971
PSY
PHYTOENE SYNTHASE; Catalyzes the reaction from prephytoene diphosphate to phytoene (437 aa)
   
  0.969
AT1G74470
Geranylgeranyl diphosphate reductase; Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis (467 aa)
   
 
  0.957
FPS1
Farnesyl diphosphate synthase 1; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (384 aa)
         
  0.952
ABC4
ABERRANT CHLOROPLAST DEVELOPMENT 4; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone (382 aa)
       
  0.946
FPS2
Farnesyl diphosphate synthase 2; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (342 aa)
         
  0.937
GPS1
Geranyl diphosphate synthase 1; May be involved in the supply of solanesyl diphosphate for ubiquinone-9 biosynthesis in mitochondria. Synthesizes C25 to C45 medium / long-chain products depending on the type of substrate available. Can use geranyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrates, but not dimethylallyl diphosphate (422 aa)
   
 
0.927
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (8%) [HD]