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FUG1 protein (Arabidopsis thaliana) - STRING interaction network
"FUG1" - Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FUG1Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal (1026 aa)    
Predicted Functional Partners:
AGY1
Protein translocase subunit SECA1, chloroplastic; Encodes the ATPase subunit of the chloroplast Sec translocation machinery which plays an essential role in chloroplast biogenesis and the regulation of photosynthesis, the absence of which triggers a retrograde signal, eventually leading to a reprogramming of chloroplast and mitochondrial gene expression (1042 aa)
 
   
  0.982
CPSRP54
Signal recognition particle 54 kDa protein, chloroplastic; Involved in cotranslational and post-translational sorting of thylakoid proteins. Binds GTP specifically. Activates the GTPase activity of CPFTSY when bound together. Required for light-harvesting chlorophyll a/b-binding protein (LHCP) integration into thylakoids (564 aa)
 
   
  0.969
EMB2761
threonyl-tRNA synthetase, putative / threonine--tRNA ligase, putative; Encodes a dual localized threonyl-tRNA synthetase found both in the mitochondrion and the chloroplast. Plants mutated in this gene terminate as embryos in the globular stage (650 aa)
   
   
  0.960
EMB1030
Alanine--tRNA ligase, chloroplastic/mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (978 aa)
 
   
  0.958
NTRC
NADPH-dependent thioredoxin reductase 3; Thioredoxin reductase (TR) that exhibits both TR and thioredoxin (Trx) activities. Contains a C-terminal functional Trx domain. Functions as an electron donor for plastidial 2-Cys peroxiredoxins and participates in a NADPH-dependent hydrogen peroxide scavenging system in chloroplasts in the dark. Required for chlorophyll biosynthesis and biogenesis of the photosynthetic apparatus. Activates aerobic cyclase which converts Mg- protoporhyrin monomethyl ester into protochlorophyllide. Involved in a light-dependent regulation of starch biosynthesis b [...] (529 aa)
   
   
  0.955
AT3G07670
Putative ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit N-methyltransferase I; Rubisco methyltransferase family protein; Its function is described as [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity; Involved in biological_process unknown; Located in chloroplast; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Rubisco methyltransferase (InterPro-IPR011192), SET domain (InterPro-IPR001214), Rubisco LSMT substrate-binding (InterPro-IPR015353); BEST Arabidopsis thaliana protein match is- Ru [...] (504 aa)
     
        0.945
AT1G57770
FAD/NAD(P)-binding oxidoreductase family protein; Its function is described as oxidoreductase activity; Located in chloroplast; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Amine oxidase (InterPro-IPR002937); BEST Arabidopsis thaliana protein match is- carotenoid isomerase (TAIR-AT1G06820.1); Has 6263 Blast hits to 6155 proteins in 967 species- Archae - 159; Bacteria - 2901; Metazoa - 394; Fungi - 76; Plants - 350; Viruses - 0; Other Eukaryotes - 2383 (source- NCBI BLink) (574 aa)
     
        0.941
ATAB2
Protein TAB2 homolog, chloroplastic; Nuclear genome-encoded A/U-rich RNA-binding protein involved in the biogenesis of photosystem I (PSI) and II (PSII). Required for the light-controlled accumulation of PSI and PSII during early plant development. Does not seem to be required for the translation of mRNAs of the PSI subunits (374 aa)
     
        0.936
AT2G27680
NAD(P)-linked oxidoreductase superfamily protein; Its function is described as oxidoreductase activity, aldo-keto reductase activity; Involved in oxidation reduction; Located in chloroplast stroma, chloroplast, chloroplast envelope, plant-type cell wall; Expressed in 24 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Aldo/keto reductase (InterPro-IPR001395); BEST Arabidopsis thaliana protein match is- NAD(P)-linked oxidoreductase superfamily protein (TAIR-AT1G06690.1); Has 12729 Blast hits to 12722 proteins in 1987 species- Archae - 303; Ba [...] (384 aa)
     
        0.936
AT5G57960
GTP-binding protein, HflX; Its function is described as GTP binding; Located in chloroplast; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Small GTP-binding protein (InterPro-IPR005225), GTP1/OBG (InterPro-IPR006073), GTP-binding protein, HflX (InterPro-IPR016496), GTP-binding protein, HSR1-related (InterPro-IPR002917); BEST Arabidopsis thaliana protein match is- GTP-binding protein, HflX (TAIR-AT3G49725.1); Has 31952 Blast hits to 30531 proteins in 2948 species- Archae - 298; Bacteria - 25096; Metazoa - 510; Fungi - 190; [...] (540 aa)
     
        0.928
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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