STRINGSTRING
GLYR2 protein (Arabidopsis thaliana) - STRING interaction network
"GLYR2" - Glyoxylate reductase 2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLYR2Glyoxylate reductase 2; Catalyzes the NADPH-dependent reduction of glyoxylate to glycolate as well as succinic semialdehyde (SSA) to gamma- hydroxybutyrate in vitro. May function in redox homeostasis and play a role in oxidative stress tolerance by detoxifying glyoxylate and SSA generated in glycolate metabolism and GABA metabolism, respectively (358 aa)    
Predicted Functional Partners:
ALDH5F1
Aldehyde dehydrogenase 5F1; Oxidizes specifically succinate semialdehyde. Involved in plant response to environmental stress by preventing the accumulation of reactive oxygen species (528 aa)
   
  0.975
AT5G36790
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Photorespiratory enzyme that dephosphorylates the 2- phosphoglycolate produced by the RuBisCO oxygenation reaction (362 aa)
     
 
  0.925
POP2
POLLEN-PISTIL INCOMPATIBILITY 2; Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate or glyoxylate as amino-group acceptor, but not 2-oxoglutarate. The pyruvate-dependent activity is reversible while the glyoxylate-dependent activity is irreversible. Cannot use beta-alanine, ornithine, acetylornithine, serine, glycine, asparagine, glutamine, glutamate, valine, leucine, isoleucine, methionine, phenylalanine, histidine, lysine, arginine, aspartate, threonine, tyrosine, tryptophan, proline, or cysteine as amino donors. Modulates steady-state GABA levels in diploid [...] (513 aa)
         
  0.913
GOX2
Glycolate oxidase 2 (373 aa)
   
 
    0.911
GOX1
Glycolate oxidase 1 (367 aa)
   
 
    0.907
ICL
Isocitrate lyase; Involved in storage lipid mobilization during the growth of higher plant seedling (576 aa)
         
  0.906
HAOX2
Aldolase-type TIM barrel family protein (363 aa)
       
    0.901
HAOX1
Aldolase-type TIM barrel family protein (363 aa)
       
    0.901
AGT2
Alanine-glyoxylate aminotransferase 2 (476 aa)
         
    0.900
PYD4
PYRIMIDINE 4 (481 aa)
         
    0.900
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]