| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AT1G66500 | AT5G43620 | AT1G66500.1 | AT5G43620.1 | Pre-mRNA cleavage complex II | Pre-mRNA cleavage complex II | 0.999 |
| AT1G66500 | AT5G60940 | AT1G66500.1 | AT5G60940.1 | Pre-mRNA cleavage complex II | transducin/WD40 domain-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA | 0.975 |
| AT1G66500 | CPSF100 | AT1G66500.1 | AT5G23880.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 100; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Required for antisense-RNA- mediated gene silencing (PubMed-17008405) | 0.984 |
| AT1G66500 | CPSF160 | AT1G66500.1 | AT5G51660.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 160; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction | 0.970 |
| AT1G66500 | CPSF30 | AT1G66500.1 | AT1G30460.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 30; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Mediates poly(A) site selection (PubMed-23136375). Binds RNA in a calcium-dependent manner (PubMed-16500995, PubMed-17576667, PubMed-20214900). Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3’ ends with hydro [...] | 0.999 |
| AT1G66500 | CPSF73-I | AT1G66500.1 | AT1G61010.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 73-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3’-end- processing endonuclease and also be involved in the histone 3’-end pre-mRNA processing | 0.966 |
| AT1G66500 | CSTF64 | AT1G66500.1 | AT1G71800.1 | Pre-mRNA cleavage complex II | Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3’ non-coding region (PubMed-12379796). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-17008405, PubMed-19965720) | 0.949 |
| AT1G66500 | CSTF77 | AT1G66500.1 | AT1G17760.1 | Pre-mRNA cleavage complex II | Tetratricopeptide repeat-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-19965720) | 0.999 |
| AT1G66500 | FIP1[V] | AT1G66500.1 | AT5G58040.1 | Pre-mRNA cleavage complex II | FIP1 [V]-like protein; Essential gene (PubMed-16282318). Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) | 0.991 |
| AT1G66500 | PAPS3 | AT1G66500.1 | AT3G06560.1 | Pre-mRNA cleavage complex II | poly(A) polymerase 3; Essential protein (PubMed-19956626). Polymerase that creates the 3’-poly(A) tail of mRNA’s (PubMed-15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) | 0.974 |
| AT5G43620 | AT1G66500 | AT5G43620.1 | AT1G66500.1 | Pre-mRNA cleavage complex II | Pre-mRNA cleavage complex II | 0.999 |
| AT5G43620 | AT5G60940 | AT5G43620.1 | AT5G60940.1 | Pre-mRNA cleavage complex II | transducin/WD40 domain-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA | 0.975 |
| AT5G43620 | CPSF100 | AT5G43620.1 | AT5G23880.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 100; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Required for antisense-RNA- mediated gene silencing (PubMed-17008405) | 0.984 |
| AT5G43620 | CPSF160 | AT5G43620.1 | AT5G51660.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 160; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction | 0.970 |
| AT5G43620 | CPSF30 | AT5G43620.1 | AT1G30460.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 30; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Mediates poly(A) site selection (PubMed-23136375). Binds RNA in a calcium-dependent manner (PubMed-16500995, PubMed-17576667, PubMed-20214900). Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3’ ends with hydro [...] | 0.839 |
| AT5G43620 | CPSF73-I | AT5G43620.1 | AT1G61010.1 | Pre-mRNA cleavage complex II | Cleavage and polyadenylation specificity factor 73-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3’-end- processing endonuclease and also be involved in the histone 3’-end pre-mRNA processing | 0.966 |
| AT5G43620 | CSTF64 | AT5G43620.1 | AT1G71800.1 | Pre-mRNA cleavage complex II | Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3’ non-coding region (PubMed-12379796). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-17008405, PubMed-19965720) | 0.949 |
| AT5G43620 | CSTF77 | AT5G43620.1 | AT1G17760.1 | Pre-mRNA cleavage complex II | Tetratricopeptide repeat-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-19965720) | 0.999 |
| AT5G43620 | FIP1[V] | AT5G43620.1 | AT5G58040.1 | Pre-mRNA cleavage complex II | FIP1 [V]-like protein; Essential gene (PubMed-16282318). Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) | 0.991 |
| AT5G43620 | PAPS3 | AT5G43620.1 | AT3G06560.1 | Pre-mRNA cleavage complex II | poly(A) polymerase 3; Essential protein (PubMed-19956626). Polymerase that creates the 3’-poly(A) tail of mRNA’s (PubMed-15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) | 0.974 |
