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EGY3 protein (Arabidopsis thaliana) - STRING interaction network
"EGY3" - Ethylene-dependent gravitropism-deficient and yellow-green-like 3 in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
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Gene Fusion
EGY3Ethylene-dependent gravitropism-deficient and yellow-green-like 3; S2P-like putative metalloprotease, also contain transmembrane helices near their C-termini and many of them, five of seven, contain a conserved zinc-binding motif HEXXH. Homolog of EGY1. Each of the EGY1 and EGY-like proteins share two additional highly conserved motifs, the previously reported NPDG motif (aa 442-454 in EGY1, Rudner et al., 1999) and a newly defined GNLR motif (aa 171-179 in EGY1). The GNLR motif is a novel signature motif unique to EGY1 and EGY-like proteins as well as other EGY1 orthologs found in cya [...] (573 aa)    
Predicted Functional Partners:
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 19 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- N2227-like (InterPro-IPR012901); BEST Arabidopsis thaliana protein match is- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR-AT2G32170.1); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; [...] (463 aa)
ATP-dependent zinc metalloprotease FTSH 6, chloroplastic; Probable ATP-dependent zinc metallopeptidase. Involved in the degradation of the light-harvesting complex of photosystem II (LHC II) during senescence or high light acclimation; In the N-terminal section; belongs to the AAA ATPase family (709 aa)
Peptide methionine sulfoxide reductase A4, chloroplastic; Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. Prevents the methionine sulfoxidation of the heat shock protein HSP21 and its subsequent inactivation. MSRA family specifically reduces the MetSO S- enantiomer (258 aa)
Membrane-bound transcription factor site-2 protease homolog; Metalloprotease that catalyzes the second step (site-2 cleavage) in the proteolytic activation of various factors, after site-1 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. After ER stress, cleaves BZIP17 and BZIP28 proteins which functions as stress sensors and transducers in ER stress signaling pathway. The N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as proteins involved in brassinosteroid (BR) signaling, which [...] (488 aa)
Galactinol synthase 1; Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. Promotes plant stress tolerance such as heat, chilling, salinity and methylviologen (MV), a superoxide radical generating drug, by mediating raffinose accumulation, an osmoprotective substance (344 aa)
HSP20-like chaperones superfamily protein; Columbia endomembrane-localized small heat shock protein (195 aa)
Delta-1-pyrroline-5-carboxylate synthase B; Encodes delta 1-pyrroline-5-carboxylate synthetase B. Gene expression is induced by dehydration, high salt and ABA. Knock-out mutations in P5CS2 are embryo-lethal. P5CS2 appears to be present in different cells and/or different subcellular locations from P5CS1 in a tissue-dependent manner; In the N-terminal section; belongs to the glutamate 5- kinase family (726 aa)
Encodes a delta1-pyrroline-5-carboxylate synthase that catalyzes the rate-limiting enzyme in the biosynthesis of proline. Gene is expressed in reproductive organs and tissues under non-stress conditions but in the whole plant under water-limiting condition. Expression is also induced by abscisic acid and salt stress in a light-dependent manner. P5CS1 appears to be involved in salt stress responses related to proline accumulation, including protection from reactive oxidative species. P5CS1 appears to be present in different cells and/or different subcellular locations from P5CS2 in a ti [...] (717 aa)
RNI-like superfamily protein; AtSKP2;2 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes. AtSKP2b may also be involved in the degradation of KRP1/ICK1, a CDK inhibitor (360 aa)
Ubiquitin-conjugating enzyme 28 (UBC28); Contains the following InterPro domains- Ubiquitin-conjugating enzyme/RWD-like (InterPro-IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro-IPR000608); BEST Arabidopsis thaliana protein match is- ubiquitin conjugating enzyme 8 (TAIR-AT5G41700.5) (190 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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