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GC2 protein (Arabidopsis thaliana) - STRING interaction network
"GC2" - Golgin candidate 2 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GC2Golgin candidate 2; This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC2 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (508-668 aa) portion of the protein (668 aa)    
Predicted Functional Partners:
GDAP1
GRIP-related ARF-binding domain-containing protein 1; This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC3 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (161 aa) portion of the protein (712 aa)
           
  0.969
SULA
Epimerase family protein SDR39U1 homolog, chloroplastic; A nuclear-encoded, plastid-targeted protein (AtSulA) whose overexpression causes severe yet stochastic plastid (shown in chloroplasts and leucoplasts) division defects. The protein does not appear to interact with either AtFtsZ proteins when studied in a yeast two-hybrid system (347 aa)
           
  0.815
GC4
Golgin candidate 4; This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC4 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (169 aa) portion of the protein (725 aa)
     
   
  0.785
AT3G43230
RING/FYVE/PHD-type zinc finger family protein; Contains the following InterPro domains- Zinc finger, FYVE-type (InterPro-IPR000306), Zinc finger, FYVE-related (InterPro-IPR017455), Zinc finger, FYVE/PHD-type (InterPro-IPR011011), Ysc84 actin-binding domain (InterPro-IPR007461); BEST Arabidopsis thaliana protein match is- RING/FYVE/PHD-type zinc finger family protein (TAIR-AT1G29800.1); Has 4080 Blast hits to 3974 proteins in 331 species- Archae - 0; Bacteria - 230; Metazoa - 2175; Fungi - 711; Plants - 392; Viruses - 3; Other Eukaryotes - 569 (source- NCBI BLink) (485 aa)
           
  0.697
EDA3
DnaJ/Hsp40 cysteine-rich domain superfamily protein; Involved in female gametophyte development. Required for embryo sac development. Nuclear genome-encoded factor required for the accumulation of photosystem I (PSI) during plant development. Required for light acclimation and chloroplast development; Belongs to the DnaJ family (186 aa)
           
  0.697
GC5
Golgin candidate 5; This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC5 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (139 aa) portion of the protein. The C-terminal portion of the protein can also specifically interact with two members of the Rab family of GTPases (RabH1b and RabH1c) (976 aa)
           
  0.611
NFS1
Cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (453 aa)
           
  0.588
AT4G40000
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Its function is described as methyltransferase activity, RNA binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 17 plant structures; Expressed during 8 growth stages; Contains the following InterPro domains- Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p (InterPro-IPR001678), Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site (InterPro-IPR018314); BEST Arabidopsis thaliana protein match is- S-adenosyl-L-methionine-dependent methyltransferases [...] (783 aa)
           
  0.588
NUDT22
Nudix hydrolase 22, chloroplastic; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family (302 aa)
           
  0.588
AT2G22400
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Its function is described as methyltransferase activity, RNA binding; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p (InterPro-IPR001678), Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site (InterPro-IPR018314); BEST Arabidopsis thaliana protein match is- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR-AT4G40000.1) [...] (808 aa)
           
  0.588
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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