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EBS5 protein (Arabidopsis thaliana) - STRING interaction network
"EBS5" - Hr.3 like protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
EBS5Hr.3 like protein; Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Functions as an ERAD substrate- recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex. Targets the misfolded LRR receptor kinase BRI1 (678 aa)    
Predicted Functional Partners:
OS9
OS9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Targets the misfolded LRR receptor kinase BRI1 and the misfolded receptor-like kinase EFR (282 aa)
     
  0.999
Hrd1A
Homolog of yeast Hrd1; Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD). Targets the misfolded LRR receptor kinase BRI1. Functions redundantly with HRD3B (492 aa)
     
  0.996
Hrd1B
Homolog of yeast Hrd1; Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD). Targets the misfolded LRR receptor kinase BRI1. Functions redundantly with HRD3A (460 aa)
     
  0.995
CDC48
Cell division cycle 48; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity) (809 aa)
     
  0.985
AtCDC48C
Cell division cycle 48C; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity) (810 aa)
     
  0.984
AtCDC48B
Cell division cycle 48B; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity) (815 aa)
     
  0.983
DER2.1
DERLIN-2.1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (244 aa)
     
  0.982
DER1
DERLIN-1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (266 aa)
       
  0.980
DER2.2
DERLIN-2.2; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (244 aa)
       
  0.980
RIN3
RPM1 interacting protein 3; E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN2. Probably not required for RPM1 degradation during HR (595 aa)
     
  0.978
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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