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STRINGSTRING
MKK7 protein (Arabidopsis thaliana) - STRING interaction network
"MKK7" - MAP kinase kinase7. Member of plant mitogen-activated protein kinase kinase group D. Negative regulator of polar auxin transport. Overexpression leads to activation of basal and systemic acquired resistance in Arabidopsis thaliana
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MKK7MAP kinase kinase7. Member of plant mitogen-activated protein kinase kinase group D. Negative regulator of polar auxin transport. Overexpression leads to activation of basal and systemic acquired resistance (307 aa)    
Predicted Functional Partners:
AT2G20050
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein; Protein serine/threonine phosphatases;protein kinases;catalytics;cAMP-dependent protein kinase regulators;ATP binding;protein serine/threonine phosphatases; Its function is described as cAMP-dependent protein kinase regulator activity, protein kinase activity, protein serine/threonine phosphatase activity, catalytic activity, ATP binding; Involved in protein amino acid phosphorylation, protein amino acid dephosphorylation, N-terminal protein myristoylation, regulation of protein amino acid phosphoryl [...] (1094 aa)
       
 
  0.857
MPK6
Mitogen-activated protein kinase 6; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Phosphorylates 1-aminocyclopropane-1- carboxylic acid synthases (ACS2 and ACS6) and may be involved in the regulati [...] (395 aa)
   
 
 
0.842
MPK12
Encodes a MAP kinase protein. MPK12 interacts with the IBR5 protein phosphatase in vitro and in vivo, and it can be dephosphorylated and inactivated by IBR5. MPK12 appears to be a negative regulator of auxin signlaing. MPK12 RNAi lines are hypersensitive to auxin in root elongation and transcriptional response assays, but they appear to have normal sensitivity to ABA. MPK12 is a nuclear protein and its kinase activity is increased following auxin treatment. MPK12 transcripts are widely expressed in seedlings, but MPK12 expression is stronger in guard cells than in other cell types in m [...] (372 aa)
   
 
 
0.785
BUD2
Adenosylmethionine decarboxylase family protein; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development (347 aa)
           
  0.778
MPK2
Mitogen-activated protein kinase homolog 2; Encodes a mitogen-activated kinase involved in innate immunity; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily (376 aa)
   
 
 
0.765
MPK15
Mitogen-activated protein kinase 15; Member of MAP Kinase; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily (576 aa)
       
 
0.701
PTP1
Protein-tyrosine-phosphatase PTP1; Protein-tyrosine-phosphatase that dephosphorylates and probably inhibits MPK6 in non-oxidative stress conditions. In association with MKP1, represses salicylic acid (SA) and camalexin biosynthesis, thus modulating defense response. May also repress MPK3. Dephosphorylates and inactivates MPK4 in vitro (340 aa)
       
 
  0.698
AT5G12850
CCCH-type zinc finger protein with ARM repeat domain; Contains the following InterPro domains- Zinc finger, CCCH-type (InterPro-IPR000571), Ankyrin repeat-containing domain (InterPro-IPR020683), Ankyrin repeat (InterPro-IPR002110); BEST Arabidopsis thaliana protein match is- CCCH-type zinc finger protein with ARM repeat domain (TAIR-AT2G41900.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source- NCBI BLink) (706 aa)
           
  0.693
AT1G11850
Uncharacterized protein At1g11850; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; Expressed in 19 plant structures; Expressed during 12 growth stages; Has 84259 Blast hits to 16502 proteins in 1194 species- Archae - 107; Bacteria - 41190; Metazoa - 21798; Fungi - 3523; Plants - 7569; Viruses - 886; Other Eukaryotes - 9186 (source- NCBI BLink) (108 aa)
           
  0.645
AT1G72550
Phenylalanine--tRNA ligase beta subunit, cytoplasmic; tRNA synthetase beta subunit family protein; Its function is described as phenylalanine-tRNA ligase activity, RNA binding, magnesium ion binding, nucleotide binding, ATP binding; Involved in phenylalanyl-tRNA aminoacylation, translation; Located in phenylalanine-tRNA ligase complex, cytoplasm; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Putative DNA binding domain (InterPro-IPR009061), tRNA synthetase, B5 (InterPro-IPR005147), Phenylalanyl-tRNA synthetase, class IIc, [...] (598 aa)
     
        0.617
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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