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MAML-4 protein (Arabidopsis thaliana) - STRING interaction network
"MAML-4" - 2-isopropylmalate synthase in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MAML-42-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Involved in Leu biosynthesis, but do not participate in the chain elongation of glucosinolates (631 aa)    
Predicted Functional Partners:
AT3G23940
Dehydratase family; Catalyzes the dehydration of 2,3-dihydroxy-3-isovalerate or 2,3-dihydroxy-3-methylvalerate to the 2-oxo acids 3-methyl-2- oxobutanoate (3MOB) or 3-methyl-2-oxopentanoate (3MOP) (608 aa)
 
 
  0.997
IIL1
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (509 aa)
   
  0.997
BCAT4
Branched-chain aminotransferase4; Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu, L-Ile and L-Val as amino donors and alpha-keto-glutarate as an amino acceptor, but no activity for D- isomers of Leu, Ile, Val, Asp, Glu or Ala. Acts on methionine and its derivatives and the corresponding 2-oxo acids. Catalyzes the initial deamination of methionine to 4-methylthio-2-oxobutyrate as well as the transamination of other typical intermediates of the methionine chain elongation pathway (354 aa)
   
  0.992
BCAT3
Branched-chain aminotransferase 3; Converts 2-oxo acids to branched-chain amino acids. Acts on leucine, isoleucine and valine. Also involved in methionine chain elongation cycle of aliphatic glucosinolate formation. Catalyzes the conversion of 5-methylthiopentyl-2-oxo and 6- methylthiohexyl-2-oxo acids to their respective Met derivatives, homomethionine and dihomo-methionine, respectively (413 aa)
   
  0.991
IPMI2
Isopropylmalate isomerase 2; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. Functions redundantly with LEUD2 in aliphatic glucosinolate biosynthesis (256 aa)
 
 
  0.989
BCAT-1
Branched-chain amino acid transaminase 1; Converts 2-oxo acids to branched-chain amino acids. Acts on leucine, isoleucine and valine (By similarity) (384 aa)
   
  0.989
IPMI1
Isopropylmalate isomerase 1; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. Functions redundantly with LEUD1 in aliphatic glucosinolate biosynthesis (253 aa)
   
 
  0.987
BCAT-2
Branched-chain amino acid transaminase 2; Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu, L-Ile and L-Val as amino donors and 2- oxoglutarate as an amino acceptor, but no activity for D-isomers of Leu, Ile, Val, Asp, Glu or Ala (388 aa)
   
  0.986
AT1G50110
Branched-chain-amino-acid aminotransferase 6; Converts 2-oxo acids to branched-chain amino acids. Acts on leucine, isoleucine and valine (By similarity) (356 aa)
   
  0.985
AT2G43090
Aconitase/3-isopropylmalate dehydratase protein; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. plays an essential role in leucine biosynthesis and female gametophyte development (251 aa)
   
 
  0.983
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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