• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
SOT17 protein (Arabidopsis thaliana) - STRING interaction network
"SOT17" - Cytosolic sulfotransferase 17 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOT17Cytosolic sulfotransferase 17; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure. Substrate preference is desulfo-benzyl glucosinolate > desulfo-6- methylthiohexyl glucosinolate. Increased specific activity with increasing chain length of desulfo-glucosinolate derived from methionine. Preferred substrate is desulfo-8-methylthiooctyl glucosinolate (346 aa)    
Predicted Functional Partners:
AKN2
Adenylyl-sulfate kinase 2, chloroplastic; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability. Required for the production of glucosinolates; Belongs to the APS kinase family (293 aa)
     
   
  0.974
APK
Adenylyl-sulfate kinase 1, chloroplastic; Encodes adenosine-5’-phosphosulfate kinase. Provides activated sulfate for sulfation of secondary metabolites, including the glucosinolates. Essential for pollen viability (276 aa)
     
   
  0.958
SUR1
Tyrosine transaminase family protein; C-S lyase involved in glucosinolate biosynthesis. Converts S-(alkylacetohydroximoyl)-L-cysteine to thiohydroximate. Functions in auxin homeostasis. Probably required for glucosinolate activation in response to pathogens; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family (462 aa)
     
   
  0.952
UGT74B1
UDP-glucosyl transferase 74B1; Involved in the biosynthesis of glucosinolate. In in vitro assay, may use phenylacetothiohydroximate (PATH), but not phenylacetic acid (PAA), indole-3-acetic acid (IAA) or salicylic acid (SA) as substrate. Specific for the thiohydroximate functional group and does not glucosylate the carboxylate group or a hydroxyl group (460 aa)
     
   
  0.944
SOT18
Desulfo-glucosinolate sulfotransferase 18; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure. Preferred substrate are the long-chain desulfo-glucosinolates, 7- methylthioheptyl and 8-methylthiooctyl, derived from methionine. Substrate preference is desulfo-benzyl glucosinolate > desulfo-4- methylthiobutyl glucosinolate > desulfo-6-methylthiohexyl glucosinolate > desulfo-3-methylthiopropyl glucosinolate > desu [...] (350 aa)
   
 
0.918
CB5-C
Cytochrome B5 isoform C; Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases (132 aa)
     
   
  0.888
SOT16
Cytosolic sulfotransferase 16; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure. Substrate preference is desulfo-2-phenylethyl glucosinolate > desulfo-indol- 3-yl methyl glucosinolate > desulfo-benzyl glucosinolate > desulfo-6-methylthiohexyl glucosinolate > desulfo-4- methylthiobutyl glucosinolate > desulfo-3-methylthiopropyl glucosinolate > desulfo-singrin > desulfo-3-butenyl glucosinolate (338 aa)
   
 
0.878
CYP79F1
Dihomomethionine N-hydroxylase; Catalyzes the conversion of the short chain elongated methionines di-, tri-, and tetrahomomethionine to their respective aldoximes 5-methylthiopentanaldoxime, 6-methylthiohexanaldoxime, and 7-methylheptanaldoxime (538 aa)
     
   
  0.877
MAM1
Encodes a methylthioalkylmalate synthase, catalyzes the condensation reactions of the first two rounds of methionine chain elongation in the biosynthesis of methionine-derived glucosinolates; Belongs to the alpha-IPM synthase/homocitrate synthase family (506 aa)
     
   
  0.875
IMS2
Methylthioalkylmalate synthase 3, chloroplastic; Determines the side chain length of aliphatic glucosinolate structures. Accepts all the omega-methylthio-2- oxoalkanoic acids needed to form the known C3 to C8 glucosinolates. Also able to convert pyruvate to citramalate, 2- oxoisovalerate to isopropylmalate, 4-methyl-2-oxopentanoate and 5- methyl-2-oxohexanoate for Leu-derived glucosinolates, 3-methyl-2- oxopentanoate for Ile-derived glucosinolates and phenylpyruvate to phenylethylglucosinolate; Belongs to the alpha-IPM synthase/homocitrate synthase family (503 aa)
     
   
  0.850
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (7%) [HD]