FMO1 protein (Arabidopsis thaliana) - STRING interaction network
"FMO1" - Flavin-dependent monooxygenase 1 in Arabidopsis thaliana
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Known Interactions
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Predicted Interactions
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FMO1Flavin-dependent monooxygenase 1; Required for the establishment of systemic acquired resistance (SAR). Not involved in local defense mechanisms. Confers a salicylic acid-dependent (SA) resistance to virulent pathogens such as P.syringae pv tomato and H.parasitica (530 aa)    
Predicted Functional Partners:
Nudix hydrolase 7 (322 aa)
Enhanced disease susceptibility 1; Positive regulator of basal resistance and of effector- triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins. Disruption by bacterial effector of EDS1-TIR- NB-LRR resistance protein interactions constitutes the first step in resistance activation (PubMed-22158819). Acts redundantly with salicylic acid to regulate resistance gene-mediated signaling (PubMed-19578402). Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of [...] (623 aa)
AGD2-like defense response protein 1; Aminotransferase involved in local and systemic acquired resistance (SAR) to the bacterial pathogen P.syringae. Required for salicylic acid (SA) and camalexin accumulation upon pathogen infection. Possesses aminotransferase activity in vitro and may generate amino-acid-derived defense signals in vivo. May be involved in ethylene-induced senescence signaling (456 aa)
AVRPPHB SUSCEPTIBLE 3; Catalyzes the conjugation of specific amino acids (e.g. Glu and possibly His, Lys, and Met) to their preferred acyl substrates (e.g. 4-substituted benzoates), in a magnesium ion- and ATP-dependent manner. Can use 4-substituted benzoates such as 4- aminobenzoate (pABA), 4-fluorobenzoate and 4-hydroxybenzoate (4- HBA), and, to a lesser extent, benzoate, vanillate and trans- cinnamate, but not 2-substituted benzoates and salicylic acid (SA), as conjugating acyl substrates. Involved in both basal and induced resistance in a SA-dependent manner. Confers resistance to [...] (575 aa)
PHYTOALEXIN DEFICIENT 4; Probable lipase required downstream of MPK4 for accumulation of the plant defense-potentiating molecule, salicylic acid, thus contributing to the plant innate immunity against invasive biotrophic pathogens and to defense mechanisms upon recognition of microbe-associated molecular patterns (MAMPs). Participates in the regulation of various molecular and physiological processes that influence fitness. Together with SG101, required for programmed cell death (PCD) triggered by NBS- LRR resistance proteins (e.g. RPS4, RPW8.1 and RPW8.2) in response to the fungal tox [...] (541 aa)
Isochorismate synthase 1; Involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death. Also involved in phylloquinone (vitamin K1) synthesis. Has no isochorismate pyruvate lyase (IPL) activity (622 aa)
Oxidoreductase, 2OG-Fe(II) oxygenase family protein; 2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD)involved in scopoletin biosynthesis. Converts feruloyl CoA into 6’-hydroxyferuloyl CoA but has no activity with ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA or benzoyl CoA (361 aa)
Cytochrome P450 71B15; Multifunctional enzyme involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes two reactions, the formation of dihydrocamalexate from indole-3-acetonitrile- cysteine conjugate and the oxidative decarboxylation of dihydrocamalexate which is the final step in camalexin biosynthesis. Required for the resistance to the fungal pathogens A.brassicicola, B.cinerea, B.elliptica, B.tulipae, L.maculans and Colletotrichum higginsianum. Seems not to be required for resistance to P.syringae, P.porri, and not involved in age-related resistance (490 aa)
Nudix hydrolase 6; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives. In vitro, it can use both NADH and ADP- ribose as substrates; however the relevance of such substrates in vivo is unclear (283 aa)
ACCELERATED CELL DEATH 11; Exhibits selective intermembrane transfer of ceramide-1- phosphate (C1P) and phytoceramide-1-phosphate (PubMed-24412362). Does not transport ceramide (Cer) or GalCer, suggesting a requirement for phosphate in the headgroup for functionality (PubMed-24412362). Transports in vitro sphingosine, but not glycosphigolipids (PubMed-11850411). Has also some in vitro activity with sphingomyelin, a lipid not detected in plant tissues (PubMed-18657186). The transport function may be not directly involved in regulating cell death. Rather, perturbations in the function of [...] (206 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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