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SK4 protein (Arabidopsis thaliana) - STRING interaction network
"SK4" - SKP1-like 4 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SK4SKP1-like 4; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F- box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F- box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity) (163 aa)    
Predicted Functional Partners:
AT3G42830
RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate (By similarity) (115 aa)
     
  0.995
CUL1
Cullin 1; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1, RBX1 and a F-box protein, it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL), SCF(ADO2/LKP2), SCF(A [...] (738 aa)
     
  0.985
RBX1
RING-box 1 (142 aa)
     
  0.977
FBP7
F-box protein 7; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Required for efficient protein synthesis during temperature stress conditions (328 aa)
       
  0.976
UBC3
Ubiquitin-conjugating enzyme 3; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (150 aa)
       
  0.969
UBC2
Ubiquiting-conjugating enzyme 2; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (152 aa)
       
  0.969
UBC1
Ubiquitin carrier protein; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (152 aa)
       
  0.969
CUL2
Cullin 2; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes. Involved in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) (742 aa)
     
  0.968
AT5G49200
Zinc finger CCCH domain-containing protein 62 (419 aa)
       
  0.964
AT5G40880
Zinc finger CCCH domain-containing protein 59 (472 aa)
       
  0.964
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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