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HMGB2 protein (Arabidopsis thaliana) - STRING interaction network
"HMGB2" - Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HMGB2Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha (144 aa)    
Predicted Functional Partners:
AT1G55650
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (337 aa)
           
  0.903
AT5G23405
HMG-box (high mobility group) DNA-binding family protein; Its function is described as DNA binding; Involved in regulation of transcription, DNA-dependent; Located in nucleus; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- High mobility group, superfamily (InterPro-IPR009071), High mobility group, HMG1/HMG2 (InterPro-IPR000910); BEST Arabidopsis thaliana protein match is- high-mobility group box 6 (TAIR-AT5G23420.1); Has 632 Blast hits to 609 proteins in 129 species- Archae - 0; Bacteria - 10; Metazoa - 212; Fungi - 44; Pla [...] (149 aa)
           
  0.739
AT4G38260
Protein of unknown function (DUF833); Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; Expressed in 22 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Protein of unknown function DUF833 (InterPro-IPR008551); BEST Arabidopsis thaliana protein match is- Protein of unknown function (DUF833) (TAIR-AT1G20680.2); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryo [...] (275 aa)
           
  0.679
AT4G37420
Domain of unknown function (DUF23); Contains the following InterPro domains- Protein of unknown function DUF23 (InterPro-IPR008166); BEST Arabidopsis thaliana protein match is- Domain of unknown function (DUF23) (TAIR-AT5G40720.1); Has 241 Blast hits to 241 proteins in 76 species- Archae - 0; Bacteria - 129; Metazoa - 0; Fungi - 0; Plants - 86; Viruses - 0; Other Eukaryotes - 26 (source- NCBI BLink) (588 aa)
           
  0.679
SPT16
Global transcription factor C; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishmen [...] (1074 aa)
     
 
  0.659
UAP56a
DEAD/DEAH box RNA helicase family protein; ATP-dependent RNA helicase involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. In addition to ssRNA and dsRNA, binds dsDNA, but not ssDNA; Belongs to the DEAD box helicase family. DECD subfamily (427 aa)
     
 
  0.644
GTC2
GTC2; Homologous to yeast SPT16, a general chromatin factor required for transcription (343 aa)
     
 
  0.626
HMGB3
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha (147 aa)
     
   
0.610
UAP56b
DEAD/DEAH box RNA helicase family protein ; Its function is described as helicase activity, nucleic acid binding, ATP binding, ATP-dependent helicase activity; Involved in biological_process unknown; Expressed in male gametophyte, guard cell, pollen tube; Expressed during M germinated pollen stage; Contains the following InterPro domains- DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro-IPR011545), RNA helicase, DEAD-box type, Q motif (InterPro-IPR014014), DEAD-like helicase, N-terminal (InterPro-IPR014001), DNA/RNA helicase, C-terminal (InterPro-IPR001650), Helicase, superfa [...] (486 aa)
     
 
  0.608
QQT1
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Encodes QQT1. Required for early embryo development. qqt1 mutant lines are embryo-defective. Participates in the organization of microtubules during cell division. Interacts with QQT2 (encoded by AT4G21800) (298 aa)
       
 
  0.604
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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