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HMGB3 protein (Arabidopsis thaliana) - STRING interaction network
"HMGB3" - High mobility group B3 in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
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Cooccurence
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[Homology]
Score
HMGB3High mobility group B3; Binds preferentially double-stranded DNA (147 aa)    
Predicted Functional Partners:
HMG
High mobility group; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the n [...] (646 aa)
       
 
  0.936
AT5G23405
HMG-box (high mobility group) DNA-binding protein (149 aa)
     
   
  0.868
SPT16
FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1074 aa)
     
 
  0.860
AT3G54470
Orotidine 5’-phosphate decarboxylase (476 aa)
       
      0.827
GTC2
Protein GTC2 (343 aa)
     
 
  0.766
AT2G30620
Histone H1.2; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures (273 aa)
     
   
  0.729
HAF01
Transcription initiation factor TFIID subunit 1-A; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex (By similarity) (1919 aa)
       
  0.706
AT3G13350
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (319 aa)
       
 
  0.671
HMGB2
High mobility group B2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses (144 aa)
     
   
0.660
KU70
KU70 homolog; Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU80, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase. Required for maintenance of the telomeric C-rich strand (621 aa)
     
      0.610
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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