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AT1G20870 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G20870" - HSP20-like chaperones superfamily protein in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G20870HSP20-like chaperones superfamily protein; Acts as an anti-silencing factor that prevents DNA hypermethylation and gene repression (PubMed-25684209) (463 aa)    
Predicted Functional Partners:
MBD7
methyl-CPG-binding domain 7; Transcriptional regulator that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. May directly affect chromatin structure by inducing intra- and inter- chromatin compaction via bridging over multiple methylated CpG sites. Acts as an anti-silencing factor that prevents DNA hypermethylation and gene repression (PubMed-25684209). Requires high mCG density for binding (PubMed-25684209, PubMed-25593350). Recognizes preferentially mCGs located in transposable elements (PubMed-25684209, PubMed-25593350). [...] (306 aa)
     
 
  0.951
ROS4
REPRESSOR OF SILENCING 4; Histone H3 acetyltransferase that binds methylated DNA at chromatin sites lacking histone H3K4 di- or trimethylation and catalyzes H3K18 and H3K23 acetylation (PubMed-22733760, PubMed-22700931). Prevents the transcriptional silencing of transgenes and of some endogenous genes (PubMed-22733760, PubMed-22700931). Requires the presence of IDM2 for efficient H3K18 acetylation, but not for H3K23 acetylation (PubMed-25002145) (1189 aa)
       
 
  0.938
AT5G02480
HSP20-like chaperone (508 aa)
           
  0.808
AT3G62470
Pentatricopeptide repeat-containing protein (599 aa)
           
  0.803
MET18
Homolog of yeast MET18; May select specific target apoproteins to which a Fe-S cluster produced by the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) pathway is transferred (1134 aa)
           
  0.737
AT1G54840
HSP20-like chaperones superfamily protein; Prevents DNA hypermethylation and transcriptional silencing of transgenes and of some endogenous genes (PubMed-25002145, PubMed-24920332). May act as a molecular chaperone of IDM1, regulating its H3K18 acetylation activity (PubMed-25002145, PubMed-24920332) (349 aa)
     
 
0.736
MBD6
methyl-CPG-binding domain 6; Transcriptional regulator that binds CpG, CpNpN and CpNpG (N is A, T, or C) islands in promoters regardless the DNA methylation status. Plays probably a role in gene silencing. May associate with histone deacetylase proteins (HDAC). Required for nucleolar dominance that consist in the silencing of rRNA genes inherited from one progenitor in genetic hybrids. Recruited to rRNA genes in a DRM2-dependent manner (225 aa)
       
 
  0.726
AT3G48425
DNAse I-like superfamily protein; Apurinic/apyrimidinic (AP) endonuclease involved in active DNA demethylation and gene imprinting (PubMed-25569774). According to a report, displays also an in vitro 3’-phosphatase activity (PubMed-25569774). According to another report, has no in vitro 3’-phosphatase activity (PubMed-25228464). Catalyzes the conversion of the 3’-blocking groups 3’-phosphor-alpha,beta- unsaturated aldehyde (3’-PUA) generated by ROS1 to 3’-OH (PubMed-25228464, PubMed-25569774). Has a strong non-specific affinity to DNA (PubMed-25228464). Redundant with APE2 and at least [...] (364 aa)
     
   
  0.710
AE7
AS1/2 ENHANCER7; Central member of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) pathway (PubMed-23104832). Involved in leaf polarity formation (PubMed-21070412). Promotes leaf adaxial identity (PubMed-21070412). May play a role in the cell cycle progression and is required for cell proliferation (PubMed-21070412) (159 aa)
           
  0.710
AT3G26742
Uncharacterized protein (51 aa)
     
   
  0.692
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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