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STRINGSTRING
ESC protein (Arabidopsis thaliana) - STRING interaction network
"ESC" - Predicted AT-hook DNA-binding family protein in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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ESCPredicted AT-hook DNA-binding family protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered FRK1 expression. Acts redundantly with AHL18, AHL22 and AHL29 in the regulation of flowering and regulation of the hypocotyl elongation. Acts as a chromatin remodeling factor that negatively regulates the leaf senescence. Acts redundantly with AHL29/SOB3 to modulate hypocotyl growth inhibition in response to light (311 aa)    
Predicted Functional Partners:
SOB3
Predicted AT-hook DNA-binding family protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Acts redundantly with AHL18, AHL22 and AHL27 in the regulation of flowering and regulation of the hypocotyl elongation. Acts redundantly with AHL27/ESC to modulate hypocotyl growth inhibition in response to light (302 aa)
     
 
0.794
FIE
Encodes a protein similar to the transcriptional regular of the animal Polycomb group and is involved in regulation of establishment of anterior-posterior polar axis in the endosperm and repression of flowering during vegetative phase. Mutation leads endosperm to develop in the absence of fertilization and flowers to form in seedlings and non-reproductive organs. Also exhibits maternal effect gametophytic lethal phenotype, which is suppressed by hypomethylation. Forms part of a large protein complex that can include VRN2 (VERNALIZATION 2), VIN3 (VERNALIZATION INSENSITIVE 3) and polyco [...] (369 aa)
           
  0.761
AT5G14130
Peroxidase superfamily protein; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue; Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily (330 aa)
     
   
  0.705
SWN
Histone-lysine N-methyltransferase EZA1; Encodes a polycomb group protein. Forms part of a large protein complex that can include VRN2 (VERNALIZATION 2), VIN3 (VERNALIZATION INSENSITIVE 3) and polycomb group proteins FERTILIZATION INDEPENDENT ENDOSPERM (FIE) and CURLY LEAF (CLF). The complex has a role in establishing FLC (FLOWERING LOCUS C) repression during vernalization. Performs a partially redundant role to MEA in controlling seed initiation by helping to suppress central cell nucleusendosperm proliferation within the FG (856 aa)
           
  0.642
VEL1
vernalization5/VIN3-like; Maybe involved in both the vernalization and photoperiod pathways by regulating gene expression. Binds preferentially to dimethylated histone H3 ’Lys-9’ (H3K9me2). Promotes flowering in non-inductive photoperiods (e.g. short days) through the maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)-dependent H3K27me3 (714 aa)
           
  0.626
VRN2
Polycomb group protein VERNALIZATION 2; The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (PcG) proteins of plants and animals. In wild-type Arabidopsis, vernalization results in the stable reduction of the levels of the floral repressor FLC. In vrn2 mutants, FLC expression is downregulated normally in response to vernalization, but instead of remaining low, FLC mRNA levels increase when plants are returned to normal temperatures. VRN2 maintains FLC repression after a cold treatment, serving as a [...] (440 aa)
           
  0.623
MES4
Methyl esterase 4; Encodes a protein shown to have carboxylesterase activity and methyl salicylate esterase activity in vitro. This protein does not act on methyl IAA, methyl JA, MeGA4, or MEGA9 in vitro; Belongs to the AB hydrolase superfamily. Methylesterase family (263 aa)
           
  0.612
MEA
Histone-lysine N-methyltransferase MEDEA; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates ’Lys-27’ of histone H3, leading to transcriptional repression of the affected target genes. Required to prevent the proliferation of the central cell of the female gametophyte by repressing target genes before fertilization. After fertilization, it probably also regulates the embryo and endosperm proliferation and anteroposterior organization during seed development. PcG proteins act by forming multiprotein complexes, which are required to maintai [...] (689 aa)
           
  0.612
VRN5
Fibronectin type III domain-containing protein; Involved in both the vernalization and photoperiod pathways by regulating expression of the related floral repressors FLOWERING LOCUS C (FLC) and FLOWERING LOCUS M (FLM). Together with VIN3, required during vernalization for the modifications of FLC and FLM chromatin that are associated with an epigenetically silenced state (e.g. chromatin modifications, histone deacetylation, and trimethylated H3 ’Lys-4’ H3K4me3 and ’Lys-27’ H3K27me3) and with acquisition of competence to flower. Promotes flowering in short days (SD=8 hours light/16 hour [...] (602 aa)
           
  0.580
RING1B
Putative E3 ubiquitin-protein ligase RING1b; Encodes a nuclear localized protein with similarity to animal polycomb repressive core complex1 (PRC1) core component RING.Appears to function redundantly with ATRING1a, a close paralog. Both interact physically with CLF and LHP1 and appear to function together to repress class I KNOX gene expression (468 aa)
           
  0.567
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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