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AT1G21580 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G21580" - Zinc finger C-x8-C-x5-C-x3-H type family protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AT1G21580Zinc finger C-x8-C-x5-C-x3-H type family protein; Its function is described as zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Zinc finger, CCCH-type (InterPro-IPR000571); Has 6412 Blast hits to 4180 proteins in 441 species- Archae - 2; Bacteria - 615; Metazoa - 1993; Fungi - 936; Plants - 1540; Viruses - 149; Other Eukaryotes - 1177 (source- NCBI BLink) (2166 aa)    
Predicted Functional Partners:
AT3G66652
Fip1 motif-containing protein; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (997 aa)
     
  0.917
ACC1
Acetyl-CoA carboxylase 1; Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways including fatty acid elongation. Required for very long chain fatty acids elongation. Necessary for embryo and plant development. Plays a central function in embryo morphogenesis, especially in apical meristem development. Involved in cell proliferation and tissue patterning. May act as a repressor of cytokinin response (2254 aa)
     
   
  0.853
HEN2
RNA helicase, ATP-dependent, SK12/DOB1 protein; ATP-dependent RNA helicase that associates with the RNA exosome complex, with the cap binding complex (CBC) and with the NEXT-like complex. Involved in the degradation of a large number of non-coding nuclear exosome substrates such as snoRNA and miRNA precursors, incompletely spliced mRNAs, and spurious transcripts produced from pseudogenes and intergenic regions. Involved in the maintenance of homeotic B and C gene expression in the reproductive whorls. Regulates floral organ spacing and identity, probably through the regulation of prote [...] (995 aa)
     
 
  0.849
PAS1
FKBP-type peptidyl-prolyl cis-trans isomerase family protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Essential protein regulating cell division, adhesion and elongation throughout the plant development and embryogenesis. Required for the spatial organization of apical meristems. Involved in the hormonal control of cell division and differentiation mediated by cytokinins and auxin. Regulates the function of NAC089 transcription factor by controlling its targeting to the nucleu [...] (635 aa)
     
   
  0.844
FIP1[V]
Homolog of yeast FIP1 [V]; Essential gene. Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) (1196 aa)
     
 
  0.837
MTR4
RNA helicase, ATP-dependent, SK12/DOB1 protein; ATP-dependent RNA helicase that associates with the RNA exosome complex. Required for proper rRNA biogenesis and development. Involved in the 3’- processing of the 7S pre-RNA to the mature 5.8S rRNA and also in the removal of rRNA maturation by-products (988 aa)
     
 
  0.835
AT5G43620
Polyadenylation and cleavage factor homolog 5; Pre-mRNA cleavage complex II; Its function is described as zinc ion binding; Involved in biological_process unknown; Located in intracellular; Contains the following InterPro domains- Zinc finger, C2H2-type (InterPro-IPR007087); BEST Arabidopsis thaliana protein match is- Pre-mRNA cleavage complex II (TAIR-AT1G66500.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source- NCBI BLink) (410 aa)
     
 
  0.825
PCFS4
Polyadenylation and cleavage factor homolog 4; Promotes flowering by suppressing FLC-mediated inhibition of flowering through the regulation of FCA pre-mRNA alternative processing. Regulates mRNA maturation including alternative polyadenylation, splicing or transcription initiation of stress-associated genes (808 aa)
     
 
  0.825
AT1G66500
Polyadenylation and cleavage factor homolog 1; Pre-mRNA cleavage complex II; Its function is described as zinc ion binding; Involved in biological_process unknown; Located in intracellular; Expressed in male gametophyte, pollen tube; Expressed during L mature pollen stage, M germinated pollen stage; Contains the following InterPro domains- Zinc finger, C2H2-type (InterPro-IPR007087); BEST Arabidopsis thaliana protein match is- Pre-mRNA cleavage complex II (TAIR-AT5G43620.1); Has 382 Blast hits to 380 proteins in 159 species- Archae - 0; Bacteria - 0; Metazoa - 108; Fungi - 132; Plants [...] (416 aa)
     
 
  0.825
CPSF160
Cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction; Belongs to the CPSF1 family (1442 aa)
     
 
  0.809
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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