STRINGSTRING
NADK2 protein (Arabidopsis thaliana) - STRING interaction network
"NADK2" - NAD kinase 2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NADK2NAD kinase 2; Involved in chlorophyll synthesis and chloroplast protection against oxidative damage (999 aa)    
Predicted Functional Partners:
NADK3
NAD(H) kinase 3; Phosphorylates specifically NADH. Can phosphorylate NAD with a 100-fold decrease in efficiency compared to NADH. Prefers ATP as nucleoside triphosphate substrate. Can also utilize UTP, GTP and CTP. Key source of the cellular reductant NADPH which is an important antioxidant factor (317 aa)
         
  0.962
AT1G55090
NAD synthetase (725 aa)
   
 
  0.949
NMNAT
Nicotinamide mononucleotide adenylyltransferase (264 aa)
   
 
  0.934
NUDX19
Nudix hydrolase 19; Mediates the hydrolysis of some nucleoside diphosphate derivatives. Has a high affinity for NADPH compared with that for NADH (438 aa)
     
 
    0.900
NADK1
NAD kinase 1; Phosphorylates both NAD(+) and NADH, with a twofold preference for NADH. Source of the cellular reductant NADPH which is an important antioxidant factor (530 aa)
         
0.833
ALDH3I1
Aldehyde dehydrogenase 3I1; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long-chain saturated aldehydes are preferred substrates, while the short-chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent (550 aa)
     
  0.698
UTR1
UDP-galactose transporter 1; Essential sugar transporter required for the transport of UDP-galactose and UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum, to ensure quality control of protein folding. Essential for pollen development and involved in embryo sac progress (332 aa)
           
  0.678
AT5G23470
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (302 aa)
           
  0.673
AT3G29760
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (465 aa)
           
  0.673
AT2G02290
Haloacid dehalogenase-like hydrolase-like protein (302 aa)
           
  0.673
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]