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AT1G22660 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G22660" - Polynucleotide adenylyltransferase-like protein in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
AT1G22660Polynucleotide adenylyltransferase-like protein (605 aa)    
Predicted Functional Partners:
AT3G26560
ATP-dependent RNA helicase, putative; May be involved in pre-mRNA splicing (1168 aa)
   
  0.983
DUF5
Uncharacterized protein (469 aa)
           
  0.910
AT5G14580
Polyribonucleotide nucleotidyltransferase; Involved in the 3’-end maturation of mitochondrial mRNAs, rRNAs and tRNAs. Functions as a poly(A) mRNA 3’-5’ degrading phosphorylase and is required for the degradation of highly expressed transcripts of non-coding regions (991 aa)
     
  0.862
RIF10
Resistant to inhibition with FSM 10; Involved in the metabolism of all major classes of plastid RNAs. Required for efficient 3’-end processing of mRNAs and 3’-end maturation of rRNA transcripts, but is not sufficient to mediate their degradation. Mediates tRNA degradation. May function as a poly(A) mRNA 3’-5’ degrading phosphorylase. May be required for plastid ribosome assembly and non-coding RNA biogenesis and accumulation. Seems not required for efficient translation (922 aa)
     
  0.854
RRP45a
Ribonuclease PH45A; Probable 3’->5’ exoribonuclease involved in the regulation of cuticular wax biosynthesis. Can perform exosomal functions and partially complement the yeast rrp45 null mutant (307 aa)
     
   
  0.838
nPAP
Nuclear poly(a) polymerase; Essential protein (PubMed-19956626). Polymerase that creates the 3’-poly(A) tail of mRNA’s (PubMed-15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) (765 aa)
     
   
  0.825
AT2G45620
Nucleotidyltransferase-like protein; UTP-RNA uridylyltransferase with a marked preference for uridine polymerization and a distributive activity for the first added nucleotides (PubMed-23748567, PubMed-25928405). Uridylates oligo(A)-tailed mRNAs to prevent 3’ to 5’ ribonucleotytic attacks (PubMed-23748567). Can prevent the 3’ trimming of mRNAs still engaged on polysomes (PubMed-23748567). Acts synergistically with HESO1 in unmethylated miRNA uridylation, leading to their degradation (PubMed-25928341). URT1 and HESO1 prefer substrates with different 3’ end nucleotides and act cooperativ [...] (764 aa)
     
 
  0.821
AT2G26970
Oligoribonuclease; 3’-to-5’ exoribonuclease specific for small oligoribonucleotides (222 aa)
         
  0.811
EMB2763
EMBRYO DEFECTIVE 2763; Catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Required for 5.8S rRNA intermediate processing and the degradation of 5’ external transcribed spacer (5’ ETS), a maturation by-product of rRNA synthesis. Is not involved in the degradation of turnip crinkle virus (TCV) RNA and significant virus resistance (PubMed-24244451). Required for normal development of female gametophytes and early embryogenesis (PubMed-20798041, PubMed-24244451) (1012 aa)
   
  0.799
EMB2730
EMBRYO DEFECTIVE 2730; 3’-5’ exoribonuclease that catalyzes 3’ maturation of chloroplast and mitochondrion ribosomal RNAs; degrades short nucleotidic extensions to generate the mature 3’-ends. Involved in the maturation of 23S, 16S and 5S rRNAs (803 aa)
   
  0.786
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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