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SUC2 protein (Arabidopsis thaliana) - STRING interaction network
"SUC2" - Sucrose-proton symporter 2 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SUC2Sucrose-proton symporter 2; Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport other glucosides such as maltose, arbutin (hydroquinone- beta-D-glucoside), salicin (2-(hydroxymethyl)phenyl-beta-D- glucoside), alpha-phenylglucoside, beta-phenylglucoside, alpha- paranitrophenylglucoside, beta-paranitrophenylglucoside, and paranitrophenyl-beta-thioglucoside. May also transport biotin. Required for apoplastic phloem sucrose loading in source tissues (e.g. leaves) in order to transport it to sink tissues (e.g. r [...] (512 aa)    
Predicted Functional Partners:
SWEET11
Nodulin MtN3-like protein; Mediates both low-affinity uptake and efflux of sugar across the plasma membrane. Involved in phloem loading by mediating export from parenchyma cells feeding H(+)-coupled import into the sieve element/companion cell complex, thus contributing to the sucrose migration from sites of synthesis in the mesophyll to the phloem (PubMed-22157085, PubMed-24027245, PubMed-25988582). Contributes to seed filling by triggering sucrose efflux involved in the transfer of sugars from seed coat to embryos (PubMed-25988582) (289 aa)
     
   
  0.746
STP1
Sugar transporter 1; Major hexose transporter. Mediates an active uptake of hexoses, by sugar/hydrogen symport. Can transport glucose, 3-O- methylglucose, fructose, xylose, mannose, galactose, fucose, 2- deoxyglucose and arabinose. Confers sensitivity to galactose in seedlings (522 aa)
           
  0.745
GLC
GLAUCE (450 aa)
           
  0.739
HXK1
Hexokinase 1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells (496 aa)
           
  0.673
SSA
Sucrose synthase 2; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and direct carbon towards starch synthesis in developing seeds (807 aa)
           
  0.670
KT2/3
Potassium transport 2/3; Highly selective and weak inward-rectifying potassium channel. Plays a role in both loading and unloading potassium into/from the phloem sap. Seems to control sugar loading into phloem via a voltage-dependent process. Blocked by physiological concentrations of external calcium and by external acidification. May interact with the cytoskeleton or with regulatory proteins. Dephosphorylation by PP2CA not only leads to the inhibition of potassium currents but also to an increase of the voltage- dependence of the channel. Regulated by the CBL4/CIPK6 calcium sensor/pr [...] (802 aa)
           
  0.670
FRU
FER-like regulator of iron uptake; Transcription factor. Essential protein involved in iron uptake responses. Regulates FRO2 at the level of mRNA accumulation and IRT1 at the level of protein accumulation. Confers enhanced iron mobilization responses at low iron supply (318 aa)
           
  0.670
HA3
H(+)-ATPase 3; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (949 aa)
     
   
  0.654
AAP2
Amino acid permease 2; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for histidine, arginine, glutamate and neutral amino acids, favoring small amino acids such as alanine, asparagine and glutamine. Accepts also large aromatic residues such as in phenlalanine or tyrosine. Has a much higher affinity for basic amino acids as compared with AAP1. May function in xylem-to-phloem transfer and in uptake of amino acids assimilated in the green silique tissue (493 aa)
     
   
  0.653
STP4
Sugar transporter 4; Mediates an active uptake of hexoses, probably by sugar/hydrogen symport. Can transport glucose, methylglucose, galactose, xylose and mannose, but not fructose (514 aa)
           
  0.636
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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