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PAB3 protein (Arabidopsis thaliana) - STRING interaction network
"PAB3" - poly(A) binding protein 3 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PAB3poly(A) binding protein 3; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Inhibits the polyadenylated RNA degradation by the Rrp41p 3’-->5’ exonuclease in vitro. Binds with the 5’UTRs of PAB2, PAB3 and with a lower affinity with the 5’UTR of PAB5 (660 aa)    
Predicted Functional Partners:
AT1G18070
G1 to S phase transition protein (543 aa)
     
  0.995
AT3G07920
Translation initiation factor IF2/IF5 (164 aa)
         
  0.973
ABH1
ABA HYPERSENSITIVE 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap str [...] (848 aa)
     
  0.972
AT4G30680
Initiation factor eIF-4 gamma, MA3 (263 aa)
     
  0.954
CBP20
CAP-binding protein 20; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structur [...] (257 aa)
     
  0.950
At5g05470
Translation initiation factor eIF-2 alpha subunit (344 aa)
     
 
  0.945
AT2G40290
Eukaryotic translation initiation factor 2 subunit 1 (344 aa)
     
 
  0.945
LBA1
LOW-LEVEL BETA-AMYLASE 1; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding (1254 aa)
       
  0.945
EIF3A
Eukaryotic translation initiation factor 3A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (987 aa)
     
  0.944
ERF1-1
Eukaryotic release factor 1-1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (PubMed-15474304). Modulates plant growth and development (PubMed-16113224) (436 aa)
     
  0.940
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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