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HIPP22 protein (Arabidopsis thaliana) - STRING interaction network
"HIPP22" - Heavy-metal-associated domain-containing protein in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
HIPP22Heavy-metal-associated domain-containing protein; Heavy-metal-binding protein. Binds cadmium. May be involved in cadmium transport and play a role in cadmium detoxification (152 aa)    
Predicted Functional Partners:
HMA5
Heavy metal atpase 5; Involved in copper import into the cell. May play a role in copper detoxification in roots (995 aa)
   
  0.927
RAN1
RESPONSIVE-TO-ANTAGONIST 1; Involved in copper import into the cell. Essential for ethylene signaling, which requires copper. Acts by delivering copper to create functional hormone receptors (1001 aa)
     
  0.925
HMA8
P-type ATPase; Mediates copper transfer across the chloroplast thylakoid membrane. Required for copper delivery into the thylakoids lumen, which is essential for the function of copper proteins (883 aa)
     
  0.925
HMA1
Heavy metal atpase 1; Involved in cadmium/zinc transport (819 aa)
     
  0.925
HMA6
P-type ATP-ase 1; Mediates copper transfer across the plastid envelope. Required for the delivery of copper into the plastid stroma, which is essential for the function of copper proteins. Seems to be selective for monovalent copper Cu(+) transport. Plays also a role in glucose signaling-mediated cell proliferation of root meristem in non-green tissues (949 aa)
     
  0.925
HMA3
Heavy metal atpase 3 (542 aa)
     
  0.925
HMA2
Heavy metal atpase 2; Plays an important role in zinc transport and homeostasis. Could also be involved in cadmium detoxification (951 aa)
     
  0.925
HMA4
Heavy metal atpase 4; Involved in cadmium/zinc transport (1172 aa)
     
  0.925
AT2G34810
FAD-binding Berberine family protein (540 aa)
           
  0.862
sks13
SKU5 similar 13 (551 aa)
       
 
  0.795
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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