STRINGSTRING
AT1G24050 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G24050" - RNA-processing, Lsm domain in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G24050RNA-processing, Lsm domain (188 aa)    
Predicted Functional Partners:
CID4
CTC-interacting domain 4 (595 aa)
       
 
  0.956
CID3
CTC-interacting domain 3 (587 aa)
       
 
  0.956
CBP20
CAP-binding protein 20; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structur [...] (257 aa)
     
      0.690
LSM1B
SM-like 1B; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5’-3’ mRNA decay. LSM1A and LSM1B are essential for the formation of the cytoplasmic LSM1-LSM7 complex which regulates developmental gene expression by the decapping of specific development-related transcripts (PubMed-23221597, PubMed-23620288). Required for P-body formation during heat stress (PubMed-23221597) (128 aa)
     
 
  0.602
AT5G14460
tRNA pseudouridine synthase B (540 aa)
       
      0.573
NAP57
Homologue of NAP57; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (’psi’) residues may serve to stabilize the conformation of rRNAs (By similarity) (565 aa)
       
      0.573
LSM2
SM-like 2; Component of LSM protein complexes, which are involved in RNA processing. Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5’-3’ mRNA decay. The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts. Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs. LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mR [...] (93 aa)
     
 
  0.524
PUM6
Pumilio 6; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3’-UTR mRNA sequence of CLV1, PNH, WUS and FAS2 (861 aa)
       
      0.493
PUM5
Pumilio 5; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3’-UTR mRNA sequence of CLV1, PNH, WUS and FAS2 (961 aa)
       
      0.493
PUM4
Pumilio 4; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3’-UTR mRNA sequence of CLV1, PNH, WUS and FAS2 (1003 aa)
       
      0.493
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]