STRINGSTRING
AT1G24250 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G24250" - Paired amphipathic helix domain-containing protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G24250Paired amphipathic helix domain-containing protein (252 aa)    
Predicted Functional Partners:
ELF6
EARLY FLOWERING 6; Acts probably as a histone ’Lys-4’ (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus (1340 aa)
     
  0.918
REF6
Relative of early flowering 6; Histone demethylase that demethylates ’Lys-27’ (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me. Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay. Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli. Involved in the regulation of flowering time by repressing FLOWERING LOCUS C (FLC) expression (1360 aa)
     
  0.918
AT4G37280
MRG family protein; Chromatin remodeling factor. Acts as a ’reader’ protein by binding to H3K36me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed-25183522, PubMed-25211338). Binds the chromatin at the FT promoter upon interaction with CO (Probable) (320 aa)
       
 
  0.897
AT1G02740
MRG family protein; Chromatin remodeling factor. Acts as a ’reader’ protein by binding to H3K4me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed-25183522, PubMed-25211338). Binds the chromatin at the FT promoter upon interaction with CO (PubMed-25211338) (327 aa)
       
 
  0.897
HAT3.1
Homeobox protein HAT3.1; Binds only to large DNA fragments. Recognizes a DNA fragment carrying 8 copies of box7 motif of the light-induced cab- E promoter of Nicotiana plumbaginifolia. Also recognizes the box7m1 motif (723 aa)
       
 
  0.895
PRHA
Pathogenesis-related homeodomain protein; Specifically binds to the fungal elicitor-responsive DNA element, 5’-CTAATTGTTTA-3’, of the gene PR2 promoter (796 aa)
       
 
  0.893
HDA7
Histone deacetylase7; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. May be involved in flowering induction. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (409 aa)
     
  0.892
AT3G13350
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (319 aa)
     
 
  0.876
AT1G76110
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (PubMed-19053246). Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed-16698901) (338 aa)
     
 
  0.876
AT1G04880
HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain; Binds preferentially DNA with A/T-rich content (448 aa)
     
 
  0.876
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (10%) [HD]