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ICME-LIKE1 protein (Arabidopsis thaliana) - STRING interaction network
"ICME-LIKE1" - Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ICME-LIKE1Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1; Catalyzes the demethylation of isoprenylcysteine methylesters. May be involved in the regulation of ABA signaling (By similarity); Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family (476 aa)    
Predicted Functional Partners:
CXE12
alpha/beta-Hydrolases superfamily protein; Encodes a protein with carboxylesterase whose activity was tested using both pNA and 2,4-D-methyl (324 aa)
   
   
  0.921
ABCD1
ABC transporter D family member 1; Contributes to the transport of fatty acids and their derivatives (acyl CoAs) across the peroxisomal membrane. Provides acetate to the glyoxylate cycle in developing seedlings. Involved in pollen tube elongation, ovule fertilization, and seeds germination after imbibition (controls the switch between the opposing developmental programs of dormancy and germination), probably by promoting beta-oxidation of storage lipids during gluconeogenesis. Required for biosynthesis of jasmonic acid and conversion of indole butyric acid to indole acetic acid. Confer [...] (1352 aa)
     
        0.748
ATSTE14B
Isoprenylcysteine carboxyl methyltransferase (ICMT) family; Encodes an isoprenyl cysteine methylatransferase (ICMT) involved in the post-translational processing of proteins that have a C-terminal CaaX box. This protein appears to have higher catalytic activity and a higher transcript expression level than the other ICMT present in Arabidopsis (At5g23320). Analysis of ICMT RNAi lines suggests that this protein is involved in flower and stem development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family (197 aa)
         
  0.649
SOBER1
Probable carboxylesterase SOBER1-like; Encodes a carboxylesterase that inhibits AvrBsT-triggered phenotypes in Arabidopsis (262 aa)
           
  0.646
CDA1
Cytidine deaminase 1; This enzyme scavenges exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis. Functions as a conventional cytidine deaminase. Has no affinity for RNA and is not involved in RNA-editing by C-to-U deamination (301 aa)
     
   
  0.634
STE14A
Protein-S-isoprenylcysteine O-methyltransferase A; Encodes a prenylcysteine alpha-carboxyl methyltransferase involved in methylation of isoprenylated proteins. This protein appears to have lower catalytic activity and a lower transcript expression level than the other ICMT present in Arabidopsis (At5g08335). Analysis of ICMT RNAi lines suggests that this protein may be involved in flower and stem development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family (197 aa)
         
  0.629
ATSTE24
Peptidase family M48 family protein; Proteolytically removes the C-terminal three residues of farnesylated proteins. The substrate specificity is only partially overlapping with that of FACE2 (424 aa)
           
  0.626
FACE2
Farnesylated protein-converting enzyme 2; Encodes an endoprotease involved in the cleavage of prenylated CaaX-box proteins. In vitro, it can cleave a farnesylated tetrapeptide and it can promote membrane-localization of a farnesylated GFP-AtROP9 protein when both are expressed in yeast; Belongs to the peptidase U48 family (311 aa)
           
  0.625
AT5G14450
GDSL-like Lipase/Acylhydrolase superfamily protein; Its function is described as hydrolase activity, acting on ester bonds, carboxylesterase activity; Involved in lipid metabolic process; Located in plant-type cell wall; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Lipase, GDSL (InterPro-IPR001087); BEST Arabidopsis thaliana protein match is- GDSL-like Lipase/Acylhydrolase superfamily protein (TAIR-AT3G26430.1); Has 3217 Blast hits to 3179 proteins in 111 species- Archae - 0; Bacteria - 82; Metazoa - 0; Fungi - 14; Plants [...] (389 aa)
           
  0.579
SFGH
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde (284 aa)
         
  0.576
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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