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CIB5 protein (Arabidopsis thaliana) - STRING interaction network
"CIB5" - Cryptochrome-interacting basic-helix-loop-helix 5 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CIB5Cryptochrome-interacting basic-helix-loop-helix 5; Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (390 aa)    
Predicted Functional Partners:
CRY2
Cryptochrome-2; Photoreceptor that mediates primarily blue light inhibition of hypocotyl elongation and photoperiodic control of floral initiation, and regulates other light responses, including circadian rhythms, tropic growth, stomata opening, guard cell development, root development, bacterial and viral pathogen responses, abiotic stress responses, cell cycles, programmed cell death, apical dominance, fruit and ovule development, seed dormancy, and magnetoreception. Photoexcited cryptochromes interact with signaling partner proteins to alter gene expression at both transcriptional a [...] (612 aa)
       
 
  0.945
CIB1
Encodes a transcription factor CIB1 (cryptochrome-interacting basic-helix-loop-helix). CIB1 interacts with CRY2 (cryptochrome 2) in a blue light-specific manner in yeast and Arabidopsis cells, and it acts together with additional CIB1-related proteins to promote CRY2-dependent floral initiation. CIB1 positively regulates FT expression (335 aa)
       
 
0.793
NUDT16
Nudix hydrolase 16, mitochondrial; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (180 aa)
           
  0.649
AT2G40200
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Its function is described as DNA binding, sequence-specific DNA binding transcription factor activity; Involved in regulation of transcription; Located in nucleus; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Helix-loop-helix DNA-binding domain (InterPro-IPR001092), Helix-loop-helix DNA-binding (InterPro-IPR011598); BEST Arabidopsis thaliana protein match is- basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR-AT3G56770.1); Has 2073 Blast hits [...] (254 aa)
           
  0.627
AT2G01820
Leucine-rich repeat protein kinase family protein; Involved in auxin signal transduction and cell expansion and proliferation regulation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (943 aa)
           
  0.618
AGL24
MADS-box protein AGL24; Transcription activator that mediates floral transition in response to vernalization. Promotes inflorescence fate in apical meristems. Acts in a dosage-dependent manner. Probably involved in the transduction of RLK-mediated signaling (e.g. IMK3 pathway). Together with AP1 and SVP, controls the identity of the floral meristem and regulates expression of class B, C and E genes. When associated with SOC1, mediates effect of gibberellins on flowering under short-day conditions, and regulates the expression of LEAFY (LFY), which links floral induction and floral deve [...] (220 aa)
           
  0.582
AT4G29930
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Its function is described as DNA binding, sequence-specific DNA binding transcription factor activity; Involved in regulation of transcription; Located in nucleus; Contains the following InterPro domains- Helix-loop-helix DNA-binding domain (InterPro-IPR001092), Helix-loop-helix DNA-binding (InterPro-IPR011598); BEST Arabidopsis thaliana protein match is- basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR-AT5G57150.1); Has 2210 Blast hits to 2206 proteins in 139 species- Archae - 0; Bacteria - 1; Metazoa - [...] (263 aa)
           
  0.580
ERF71
Ethylene-responsive transcription factor ERF071; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity) (171 aa)
           
  0.580
NUDX13
Nudix hydrolase 13, mitochondrial; Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use diadenosine 5’,5’’’-P(1)P(6) hexaphosphate (Ap(6)A), diadenosine 5’,5’’’-P(1)P(5) pentaphosphate (Ap(5)A) and adenosine tetraphosphate (p(4)A) as substrates, but not diadenosine 5’,5’’’-P(1)P(4) tetraphosphate (Ap(4)A), diadenosine 5’,5’’’-P(1)P(3) triphosphate (Ap(3)A), deoxyribonucleoside triphosphates, ribonucleoside triphosphates, diphosphoinositol pentakisphosphate (PP-InsP(5)) and 5-phospho-alpha-D-ribosyl diphosphate (PRPP); Belongs to the Nudix hydrolase family (202 aa)
           
  0.576
NUDT12
Nudix hydrolase 12, mitochondrial; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family (203 aa)
           
  0.576
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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