STRINGSTRING
UPS5 protein (Arabidopsis thaliana) - STRING interaction network
"UPS5" - Ureide permease 5 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UPS5Ureide permease 5; Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Mediates transport of uracil and 5-fluorouracil (a toxic uracil analog) (413 aa)    
Predicted Functional Partners:
PHT4;5
Phosphate transporter 4;5; Inorganic phosphate and probable anion transporter (517 aa)
           
  0.805
AT2G26230
Urate oxidase; Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (309 aa)
           
  0.679
ALN
Allantoinase; Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoate by hydrolytic cleavage of the five- member hydantoin ring. Catalyzes the first step of the ureide allantoin degradation followed by the sequential activity of AAH, UGLYAH and UAH which allows a complete purine berakdown without the intermediate generation of urea (506 aa)
           
  0.678
AMT1;4
Ammonium transporter 1;4; High affinity ammonium transporter in the plasma membrane (504 aa)
           
  0.672
NCS1
Nucleobase cation symporter 1; Nucleobase-proton symporter that facilitates the uptake of nucleobases in the cells. Can transport adenine, guanine and uracil (PubMed-22616996, PubMed-22474184, PubMed-24621654). Contributes to uracil import into plastids for plastidic uracil salvage which is essential for plant growth and development (PubMed-22474184) (599 aa)
           
  0.632
PUT4
POLYAMINE UPTAKE TRANSPORTER 4; Probable cell membrane polyamine/proton symporter involved in the polyamine uptake in cells (478 aa)
           
  0.631
AAP6
Amino acid permease 6; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for tryptophan, proline, and neutral and acidic amino acids. Have an affinity for aspartate in a physiological range. Involved in the uptake of amino acids diffusing out of the xylem tracheids into the xylem parenchyma (481 aa)
           
  0.491
NAK
Putative serine/threonine-protein kinase NAK; May play a role in the regulation of plant growth and development (389 aa)
           
  0.480
AAP2
Amino acid permease 2; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for histidine, arginine, glutamate and neutral amino acids, favoring small amino acids such as alanine, asparagine and glutamine. Accepts also large aromatic residues such as in phenlalanine or tyrosine. Has a much higher affinity for basic amino acids as compared with AAP1. May function in xylem-to-phloem transfer and in uptake of amino acids assimilated in the green silique tissue (493 aa)
           
  0.443
AT1G72390
Uncharacterized protein (1325 aa)
           
  0.442
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (7%) [HD]